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Sustainable Material For Urea Delivery Based On Chitosan Cross-Linked By Glutaraldehyde Saturated Toluene: Characterization And Determination Of The Release Rate Mathematical Model, Jayanudin Jayanudin, Retno S. D. Lestari, Indar Kustiningsih, Dandi Irawanto, Rozak Rozak, Reyonaldo L. A. Wardana, Fakhri Muhammad
Sustainable Material For Urea Delivery Based On Chitosan Cross-Linked By Glutaraldehyde Saturated Toluene: Characterization And Determination Of The Release Rate Mathematical Model, Jayanudin Jayanudin, Retno S. D. Lestari, Indar Kustiningsih, Dandi Irawanto, Rozak Rozak, Reyonaldo L. A. Wardana, Fakhri Muhammad
Karbala International Journal of Modern Science
The aims of this study were to characterize the urea-loaded chitosan microspheres and determine the release kinetic constants and diffusion coefficients. An emulsion cross-linking method was used to prepare the urea-loaded chitosan microspheres. Urea was dissolved in a solution of chitosan then put into vegetable oil and stirred to form an emulsion. Glutaraldehyde saturated toluene (GST) was added into the emulsion dropwise while continuously stirring for the solidification process. Chitosan microspheres filled with urea were washed, dried, and then analyzed. Characterization of the urea-loaded chitosan microspheres was conducted using a scanning electron microscope (SEM), Raman spectroscopy, X-ray diffraction, and particle …