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Articles 1 - 7 of 7
Full-Text Articles in Chemical Engineering
Ordered Network Phases In Linear Poly(Isoprene-B-Styrene-B-Ethylene Oxide) Triblock Copolymers, Thomas H. Epps Iii, Eric W. Cochran, Travis S. Bailey, Ryan S. Waletzko, Cordell M. Hardy, Frank S. Bates
Ordered Network Phases In Linear Poly(Isoprene-B-Styrene-B-Ethylene Oxide) Triblock Copolymers, Thomas H. Epps Iii, Eric W. Cochran, Travis S. Bailey, Ryan S. Waletzko, Cordell M. Hardy, Frank S. Bates
Eric W. Cochran
The equilibrium phase behavior of 43 linear poly(isoprene-b-styrene-b- ethylene oxide) (ISO) triblock copolymer melts, with molecular weights that place these materials near the order-disorder transition, is reported. Ordered phase morphologies were characterized using small-angle X-ray scattering, transmission electron microscopy, dynamic mechanical spectroscopy, and static birefringence measurements. Interpretation of these results was aided by a modeling technique that facilitates resolution of reciprocal and real-space experimental data, leading to definitive three-dimensional morphological structures. Three distinct multiply continuous network morphologies are identified across a range of compositions between 0.1 ≤ f o ≤ 0.3, situated between two-domain and three-domain lamellae, where f o …
Biomolecule-Directed Assembly Of Nanoscale Building Blocks Studied Via Lattice Monte Carlo Simulation, Ting Chen, Monica H. Lamm, Sharon C. Glotzer
Biomolecule-Directed Assembly Of Nanoscale Building Blocks Studied Via Lattice Monte Carlo Simulation, Ting Chen, Monica H. Lamm, Sharon C. Glotzer
Monica H. Lamm
The self-assembly of functionalized inorganic nanoscale building blocks (NBB) was investigated using recognitive biomolecule linkers. The NBBs and linkers were studied using bond fluctuation model and algorithm on a simple cubic lattices. The loops contained in the soluble material to avoid double counting when calculating the fraction of loops. The algorithm was used to calculate additional network properties when volume fractions above the percolation threshold was simulated.
Network Phases In Abc Triblock Copolymers, Thomas H. Epps Iii, Eric W. Cochran, Cordell M. Hardy, Travis S. Bailey, Ryan S. Waletzko, Frank S. Bates
Network Phases In Abc Triblock Copolymers, Thomas H. Epps Iii, Eric W. Cochran, Cordell M. Hardy, Travis S. Bailey, Ryan S. Waletzko, Frank S. Bates
Eric W. Cochran
Many naturally occurring and engineered products are influenced by network structures. Collagen networks provide a scaffold for living tissue, while swollen arrays of physically cross-linked polypeptides constitute gelatin, the familiar dessert and electrophoresis medium. Although the associated mesh sizes differ by several orders of magnitude, these examples share a common feature: three-dimensional connectivity that imparts mechanical rigidity. Intercalating additional interconnected components can yield broader functions, e.g., ionic or electrical conductivity, optical band gaps, and tailored heat and mass transfer.
Shear-Induced Network-To-Network Transition In A Block Copolymer Melt, Eric W. Cochran, Frank S. Bates
Shear-Induced Network-To-Network Transition In A Block Copolymer Melt, Eric W. Cochran, Frank S. Bates
Eric W. Cochran
The tricontinuous (10, 3)c shear-induced network-to-network transition in a block copolymer melt was analyzed using small-angle x-ray scattering. Investigations show that field-induced network-to-network phase transition was unprecedented in soft condensed matter. It was found that shear transforms were used for self-assembling the soft material into a single crystal (10, 3)d network. The results show the delicate nature of block copolymers phase behavior, where candidate morphologies were spaced closely together on the free energy surface.
Consequences Of Block Number On The Order-Disorder Transition And Viscoelastic Properties Of Linear (Ab)N Multiblock Copolymers, Lifeng Wu, Eric W. Cochran, Timothy P. Lodge, Frank S. Bates
Consequences Of Block Number On The Order-Disorder Transition And Viscoelastic Properties Of Linear (Ab)N Multiblock Copolymers, Lifeng Wu, Eric W. Cochran, Timothy P. Lodge, Frank S. Bates
Eric W. Cochran
The effect of block number on the order-disorder transition (ODT) and viscoelastic properties were studied for linear (AB) n multiblock copolymers. A series of symmetric poly(styrene-b-isoprene) n multiblocks ((SI) n, n = 1-10) were synthesized by anionic polymerization, and their order-disorder transition temperatures (T ODT) were located using dynamic mechanical spectroscopy. As n increases, T ODT approaches an asymptotic value, consistent with random phase approximation calculations. A systematic difference between the experimental and theoretical results is attributable to the effects of fluctuations, independent of the number of blocks. Addition of up to 20 vol % of a nonselective solvent depresses …
Rational Pathway Engineering Of Type I Fatty Acid Synthase Allows The Biosynthesis Of Triacetic Acid Lactone From D-Glucose In Vivo, Wenjuan Zha, Zengyi Shao, John W. Frost, Huimin Zhao
Rational Pathway Engineering Of Type I Fatty Acid Synthase Allows The Biosynthesis Of Triacetic Acid Lactone From D-Glucose In Vivo, Wenjuan Zha, Zengyi Shao, John W. Frost, Huimin Zhao
Zengyi Shao
Metabolic pathway engineering is a powerful tool to synthesize structurally diverse and complex chemicals via genetic manipulation of multistep catalytic systems involved in cell metabolism. Here, we report the rational design of a fatty acid biosynthetic pathway, Brevibacterium ammoniagenes fatty acid synthase B (FAS-B), that allows the microbial synthesis of triacetic acid lactone (TAL) from an inexpensive feedstock, D-glucose. TAL can be chemically converted to phloroglucinol, which is a core structure for the synthesis of various high value bioactive compounds and energetic compounds such as 1,3,5-triamino-2,4,6-trinitrobenzene (TATB). Synthesis of phloroglucinol from d-glucose using this combined biological and chemical synthesis may …
Spatial Analysis Of 3′ Phosphoinositide Signaling In Living Fibroblasts: Ii. Parameter Estimates For Individual Cells From Experiments, Ian C. Schneider, Jason M. Haugh
Spatial Analysis Of 3′ Phosphoinositide Signaling In Living Fibroblasts: Ii. Parameter Estimates For Individual Cells From Experiments, Ian C. Schneider, Jason M. Haugh
Ian C. Schneider
Fibroblast migration is directed by gradients of platelet-derived growth factor (PDGF) during wound healing. As in other chemotactic systems, it has been shown recently that localized stimulation of intracellular phosphoinositide (PI) 3-kinase activity and production of 3′ PI lipids in the plasma membrane are important events in the signaling of spatially biased motility processes. In turn, 3′ PI localization depends on the effective diffusion coefficient, D, and turnover rate constant, k, of these lipids. Here we present a systematic and direct comparison of mathematical model calculations and experimental measurements to estimate the values of the effective 3′ PI diffusion coefficient, …