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Lignocellulosic And Cellulosic Beads For Affinity And Immunoaffinity Chromatography Of High Molecular Weight Protiens, William H. Velander
Lignocellulosic And Cellulosic Beads For Affinity And Immunoaffinity Chromatography Of High Molecular Weight Protiens, William H. Velander
Department of Chemical and Biomolecular Engineering: Patents
Improved cellulosic beads for use as supports in bioaffinity chromatography are produced by dissolution of cellulose in a chaotropic cellulose solvent, formation of the dissolved cellulose into droplets, and immersion of the droplets into a non-solvent capable of solvent interchange with the cellulose solvent to form generally spherical porous cellulose beads of narrow particle size distribution. The beads formed are preferably made with cellulose having a degree of polymerization between 100 and 200, and the resulting beads when saturated with water without drying contain between 1% and 7% cellulose by weight and have a particle size of at least about …