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Articles 1 - 30 of 678
Full-Text Articles in Chemical Engineering
Consistent Intraocular Pressure Reduction By Solid Drug Nanoparticles In Fixed Combinations For Glaucoma Therapy, Da Huang, Pedro Norat, Lin Qi, Anna Chernatynskaya, James D. Cole, Vimalin Jeyalatha Mani, Lei Xu, Xiaorong Liu, Hu Yang
Consistent Intraocular Pressure Reduction By Solid Drug Nanoparticles In Fixed Combinations For Glaucoma Therapy, Da Huang, Pedro Norat, Lin Qi, Anna Chernatynskaya, James D. Cole, Vimalin Jeyalatha Mani, Lei Xu, Xiaorong Liu, Hu Yang
Chemical and Biochemical Engineering Faculty Research & Creative Works
Efficient topical drug delivery remains a significant challenge in glaucoma management. Although nanoparticle formulations offer considerable promise, their complex preparation processes, co-delivery issues, and batch consistency have hindered their potential. A scalable fabrication strategy is developed here for preparing solid drug nanoparticles (SDNs) with enhanced drug delivery efficiency. Utilizing hydrophobic antiglaucoma drugs brimonidine (BM) and betaxolol (BX), uniform fixed combination BM/BX SDNs are fabricated through a continuous process, improving batch-to-batch consistency for combined glaucoma treatment. With trehalose being used as a lyoprotectant, BM/BX SDNs can be stored as dry powder and easily reconstituted in phosphate buffered saline. Importantly, reconstituted BM/BX …
Determination Of Binary Co2/H2 Adsorption Isotherms And Kinetics Over Porous Organic Cage Cc3 Via Zero-Length Column Technique, Jimmy D.L. Moreno, Kyle Newport, Ali A. Rownaghi, Fateme Rezaei
Determination Of Binary Co2/H2 Adsorption Isotherms And Kinetics Over Porous Organic Cage Cc3 Via Zero-Length Column Technique, Jimmy D.L. Moreno, Kyle Newport, Ali A. Rownaghi, Fateme Rezaei
Chemical and Biochemical Engineering Faculty Research & Creative Works
Understanding the dynamics of mixed-gas adsorption is essential for industrial-scale adsorptive separations. Also, obtaining binary adsorption isotherms is essential to gain a better understanding of adsorbate-adsorbent interactions in multicomponent gas mixtures. Porous organic cages (POCs) are highly porous, crystalline materials, with a small average pore window that make them promising candidates for separation applications. In this work, we utilized zero-length column (ZLC) technique to not only determine the kinetics of CO2/H2 separation over CC3 but also obtain the binary adsorption isotherms. The ultra crystalline diffusivities of 1.49 x 10–4 and 8.31 x 10–5 cm2 …
Design And Development Of Uio-67-Coated Pim-1-Based Composites And Demonstration Of Their Detoxification Performance, Sukanta K. Mondal, Peter O. Aina, Ali A. Rownaghi, Fateme Rezaei
Design And Development Of Uio-67-Coated Pim-1-Based Composites And Demonstration Of Their Detoxification Performance, Sukanta K. Mondal, Peter O. Aina, Ali A. Rownaghi, Fateme Rezaei
Chemical and Biochemical Engineering Faculty Research & Creative Works
Polymer-supported MOF composites have emerged as versatile candidates for various separation and catalytic applications. In this study, we demonstrate design and development of UiO-67-coated Ce(OH)4@PIM-1 composites via dip-coating, drop-casting, solid-phase coating, and supramolecular assembly, and assess their preparation-structure-performance relations. The catalytic performance of the composites was investigated through hydrolysis of dimethyl 4-nitrophenyl phosphate (DMNP), as a nerve agent simulant. The findings revealed that while dip-coating method was unable to achieve a thick and uniform coverage of the MOF layer on the Ce(OH)4@PIM-1, the supramolecular assembly gave rise to 16 wt.% MOF loading and the composite prepared …
Emulsion Liquid Membrane (Elm) Enhanced By Nanoparticles And Ionic Liquid For Extracting Vanadium Ions From Wastewater, Qusay Al-Obaidi, Nora Yehia Selem, Muthanna H. Al-Dahhan
Emulsion Liquid Membrane (Elm) Enhanced By Nanoparticles And Ionic Liquid For Extracting Vanadium Ions From Wastewater, Qusay Al-Obaidi, Nora Yehia Selem, Muthanna H. Al-Dahhan
Chemical and Biochemical Engineering Faculty Research & Creative Works
Emulsion liquid membrane (ELM) stands out as an extraction process that has drawn much attention due to its promising prospects in industrial wastewater treatment technology. Nevertheless, the pivotal challenge is to reach high membrane stability to overcome the obstacle of applying ELM at the industrial scale. In this study, ELM was boosted by using nanoparticles (superparamagnetic iron oxide (Fe2O3)) in the stripping phase (W1) and ionic liquid (1-methyl-3-octyl-imidazolium-hexafluorophosphate [OMIM][PF6) in the oil phase (O) for recovering/extracting vanadium from synthetic wastewater to near completion and at the same time enhancing emulsion stability to be appropriate for industrial …
Experimental Investigation Of Liquid Holdup In A Co-Current Gas–Liquid Upflow Moving Packed Bed Reactor With Porous Catalyst Using Gamma-Ray Densitometry, Ali Toukan, Ahmed Jasim, Vineet Alexander, Hamza Albazzaz, Muthanna H. Al-Dahhan
Experimental Investigation Of Liquid Holdup In A Co-Current Gas–Liquid Upflow Moving Packed Bed Reactor With Porous Catalyst Using Gamma-Ray Densitometry, Ali Toukan, Ahmed Jasim, Vineet Alexander, Hamza Albazzaz, Muthanna H. Al-Dahhan
Chemical and Biochemical Engineering Faculty Research & Creative Works
This study explores the dynamics of liquid holdup in a lab-scale co-current two-phase up flow moving packed bed reactor, specifically examining how superficial gas velocity influences the line average external liquid holdup at a fixed superficial liquid velocity. Utilizing gamma-ray densitometry (GRD) for precise measurements, this research extends to determining line average internal porosity within catalyst particles. Conducted with an air–water system within a bed packed with 3 mm porous particles, the study presents a novel methodology using Beer–Lambert's law to calculate liquid, gas, and solid holdups and catalyst porosity that is equivalent to the internal liquid holdup that fills …
Kinetic Studies Of Liquid Phase Hydrogenation Of Acetylene For Ethylene Production Using A Selective Solvent Over A Commercial Palladium/Alumina Catalyst, Humayun Shariff, Muthanna H. Al-Dahhan
Kinetic Studies Of Liquid Phase Hydrogenation Of Acetylene For Ethylene Production Using A Selective Solvent Over A Commercial Palladium/Alumina Catalyst, Humayun Shariff, Muthanna H. Al-Dahhan
Chemical and Biochemical Engineering Faculty Research & Creative Works
The Kinetics of Selective Hydrogenation of Acetylene in the Liquid Phase over a Commercial 0.5 Wt % Pd/Al2O3 Spherical Catalyst Was Investigated in a Stirred-Tank Basket Reactor. the Liquid Phase Was Acetylene Gas Absorbed in a Selective Solvent, N-Methylpyrrolidone (NMP). the Reactor Was Operated at a Pressure Range of 15-250 Psig with Temperature Varying from 60 to 100 °C using Different Catalyst Loadings to Identify the Suitable Operating Conditions. the Kinetic Experiments Were Conducted in the Absence of External Mass Transfer Resistances with the Liquid Phase in Batch Mode and the Gas Phase Being Continuous. the Initial Rates Varied Linearly …
Localized Sustained Release Of Copper Enhances Antitumor Effects Of Disulfiram In Head And Neck Cancer, Juan Wang, Boxuan Li, Remy C. Cooper, Da Huang, Hu Yang
Localized Sustained Release Of Copper Enhances Antitumor Effects Of Disulfiram In Head And Neck Cancer, Juan Wang, Boxuan Li, Remy C. Cooper, Da Huang, Hu Yang
Chemical and Biochemical Engineering Faculty Research & Creative Works
Drug Repurposing Uses Approved Drugs as Candidate Anticancer Therapeutics, Harnesses Previous Research and Development Efforts, and Benefits from Available Clinically Suitable Formulations and Evidence of Patient Tolerability. in This Work, the Drug Used Clinically to Treat Chronic Alcoholism, Disulfiram (DSF), Was Studied for its Antitumor Efficacy in a Copper-Dependent Manner. the Combination of DSF and Copper Could Achieve a Tumor Cell Growth Inhibition Effect Comparable to Those of 5-Fluorouracil and Taxol on Head and Neck Cancer Cells. Both Bulk Dendrimer Hydrogel and Microsized Dendrimer Hydrogel Particles Were Utilized for the Localized Sustained Release of Copper in the Tumor Site. the …
Liquid-Phase Adsorption Of Dimethyl Methylphosphonate On Poly(Ether Imide) And Its Metal Hydroxide-Integrated Composites, Sukanta K. Mondal, Peter O. Aina, Ali A. Rownaghi, Fateme Rezaei
Liquid-Phase Adsorption Of Dimethyl Methylphosphonate On Poly(Ether Imide) And Its Metal Hydroxide-Integrated Composites, Sukanta K. Mondal, Peter O. Aina, Ali A. Rownaghi, Fateme Rezaei
Chemical and Biochemical Engineering Faculty Research & Creative Works
Understanding the Adsorption Behavior of Dimethyl Methylphosphonate (DMMP), a Key Simulant for Some Nerve Agents, is Crucial for Developing Effective Protective Measures and Ensuring Environmental Safety Against Harmful Chemical Warfare Agents. This Study Systematically Explores the Liquid-Phase Adsorption of DMMP over Branched Poly (Ether Imide) (Ultem) and its Ce (OH)4/Zr (OH)4 Metal Hydroxide Composites. Utilizing UV-Visible (UV-Vis) Spectroscopy, the Adsorption Process Was Monitored over Time to Analyze the Interplay between Various Ultem-Based Composites and DMMP Molecules. Nonreactive Ultem Materials Were Experimentally Identified as Suitable Adsorbents for Liquid-Phase DMMP Capture, Providing a Novel Avenue for Protective Filtration Technologies. It Was Found …
Cooperative And Bifunctional Adsorbent-Catalyst Materials For In-Situ Vocs Capture-Conversion, Sukanta K. Mondal, Peter Aina, Ali A. Rownaghi, Fateme Rezaei
Cooperative And Bifunctional Adsorbent-Catalyst Materials For In-Situ Vocs Capture-Conversion, Sukanta K. Mondal, Peter Aina, Ali A. Rownaghi, Fateme Rezaei
Chemical and Biochemical Engineering Faculty Research & Creative Works
Volatile Organic Compounds (VOCs) Are Gases that Are Emitted into the Air from Products or Processes and Are Major Components of Air Pollution that Significantly Deteriorate Air Quality and Seriously Affect Human Health. Different Types of Metals, Metal Oxides, Mixed-Metal Oxides, Polymers, Activated Carbons, Zeolites, Metal-Organic Frameworks (MOFs) and Mixed-Matrixed Materials Have Been Developed and Used as Adsorbent or Catalyst for Diversified VOCs Detection, Removal, and Destruction. in This Comprehensive Review, We First Discuss the General Classification of VOCs Removal Materials and Processes and Outline the Historical Development of Bifunctional and Cooperative Adsorbent-Catalyst Materials for the Removal of VOCs from …
Future Of Process Safety: Insights, Approaches, And Potential Developments, Hossein Abedsoltan, Amirhesam Abedsoltan, Zeinab Zoghi
Future Of Process Safety: Insights, Approaches, And Potential Developments, Hossein Abedsoltan, Amirhesam Abedsoltan, Zeinab Zoghi
Chemical and Biochemical Engineering Faculty Research & Creative Works
This review explores the evolving landscape of process safety, emphasizing the integration of digitalization and advanced technologies. It assesses the role of the industrial Internet of Things, artificial intelligence, and machine learning (ML) in enhancing safety protocols. The paper examines predictive analytics, sensor technology advancements, and digital twins' contributions to safety optimization. It also discusses the future perspectives of risk management approaches, including proactive safety management systems, quantitative risk assessment techniques, and human reliability analysis. This comprehensive analysis provides insights into future developments and challenges in process safety.
L-Ergothioneine Slows The Progression Of Age-Related Hearing Loss In Cba/Caj Mice, Mark A. Bauer, Parveen Bazard, Alejandro A. Acosta, Nidhi Bangalore, Lina Elessaway, Mark Thivierge, Moksheta Chellani, Xiaoxia Zhu, Bo Ding, Joseph P. Walton, Robert D. Frisina
L-Ergothioneine Slows The Progression Of Age-Related Hearing Loss In Cba/Caj Mice, Mark A. Bauer, Parveen Bazard, Alejandro A. Acosta, Nidhi Bangalore, Lina Elessaway, Mark Thivierge, Moksheta Chellani, Xiaoxia Zhu, Bo Ding, Joseph P. Walton, Robert D. Frisina
Chemical and Biochemical Engineering Faculty Research & Creative Works
The naturally occurring amino acid, l-ergothioneine (EGT), has immense potential as a therapeutic, having shown promise in the treatment of other disease models, including neurological disorders. EGT is naturally uptake into cells via its specific receptor, OCTN1, to be utilized by cells as an antioxidant and anti-inflammatory. In our current study, EGT was administered over a period of 6 months to 25–26-month-old CBA/CaJ mice as a possible treatment for age-related hearing loss (ARHL), since presbycusis has been linked to higher levels of cochlear oxidative stress, apoptosis, and chronic inflammation. Results from the current study indicate that EGT can prevent aging …
Seeding Effects Of Submicron Caal-No3 Ldh Particles On The Hydration And Properties Of Portland Cement And Sulfoaluminate Cement Pastes, Sukanta K. Mondal, Monday Uchenna Okoronkwo
Seeding Effects Of Submicron Caal-No3 Ldh Particles On The Hydration And Properties Of Portland Cement And Sulfoaluminate Cement Pastes, Sukanta K. Mondal, Monday Uchenna Okoronkwo
Chemical and Biochemical Engineering Faculty Research & Creative Works
Layered Double Hydroxide (LDH) Is Reported To Improve The Durability Of Concretes, Primarily Due To Its Ability To Exchange Anionic Species, Including Chloride, Which Is Implicated In Corrosion-Driven Durability Issues. However, There Is No Comprehensive Study Investigating The Effect Of LDH On The Properties Of Different Cement Systems At Both Early And Mature Ages. In This Study, The Early Age And Mature Age Properties Of Portland Cement (OPC) And Calcium Sulfoaluminate (CSA) Cement Pastes Seeded With Submicron-Sized Calcium Aluminum-NO3 LDH (CaAl-NO3 LDH) Were Investigated. The Effects Of The 1–5%mass Dosage Of LDH On The Hydration Of Both Cement Systems Were …
Assessing Hydrolysis Performance Of Ce(Oh)4@Pim-1 Composites Functionalized With Amidoxime, Aldoxime, And Carboxylate Groups Toward Dimethyl 4-Nitrophenylphosphonate, A Nerve Agent Simulant, Peter O. Aina, Sukanta K. Mondal, Ali A. Rownaghi, Fateme Rezaei
Assessing Hydrolysis Performance Of Ce(Oh)4@Pim-1 Composites Functionalized With Amidoxime, Aldoxime, And Carboxylate Groups Toward Dimethyl 4-Nitrophenylphosphonate, A Nerve Agent Simulant, Peter O. Aina, Sukanta K. Mondal, Ali A. Rownaghi, Fateme Rezaei
Chemical and Biochemical Engineering Faculty Research & Creative Works
In recent years, significant attention has been directed toward evaluating the reactivity of diverse polymers to gauge their catalytic activity against hazardous chemicals. Among these polymers, pim-1 has emerged as an exceptional candidate due to its noteworthy attributes including high surface area, excellent solubility, and the capability to fine-tune the nitrile functional groups along its polymeric backbone. In this study, we explored the impact of different functional groups, such as amidoxime (ax), aldoxime (ox), and carboxylate (cooh), on the degradation of dimethyl 4-nitrophenylphosphonate (dmnp) in comparison to pure pim-1 and their respective ce(oh)4-loaded polymer composites. Remarkably, the pim-1-ax analog exhibited …
Mitigation Of Potential Risks In Chemical Laboratories: A Focused Review, Hossein Abedsoltan, Mark B. Shiflett
Mitigation Of Potential Risks In Chemical Laboratories: A Focused Review, Hossein Abedsoltan, Mark B. Shiflett
Chemical and Biochemical Engineering Faculty Research & Creative Works
This review paper presents an analysis of safety practices in chemical laboratories. It encompasses a systematic exploration of various facets including risk assessment, hazard mitigation, and the implementation of safety protocols. Emphasis is placed on the critical role of continuous education and training, advocating a proactive safety culture, and adapting to technological advancements. Additionally, the paper underscores the importance of adhering to regulatory standards, promoting exceeding baseline compliance toward establishing best practices in laboratory safety. This comprehensive approach highlights the dynamic, multifaceted nature of laboratory safety, positioning it as a fundamental aspect of scientific research.
Highly Efficient Dopamine Sensing With A Carbon Nanotube-Encapsulated Metal Chalcogenide Nanostructure, Harish Singh, Jiandong Wu, Kurt A.L. Lagemann, Manashi Nath
Highly Efficient Dopamine Sensing With A Carbon Nanotube-Encapsulated Metal Chalcogenide Nanostructure, Harish Singh, Jiandong Wu, Kurt A.L. Lagemann, Manashi Nath
Chemical and Biochemical Engineering Faculty Research & Creative Works
Carbon nanotube-encapsulated nickel selenide composite nanostructures were used as nonenzymatic electrochemical sensors for dopamine detection. These composite nanostructures were synthesized through a simple, one-step, and environmentally friendly chemical vapor deposition method, wherein the CNTs were formed in situ from pyrolysis of a carbon-rich metallo-organic precursor. The composition and morphology of these hybrid NiSe2-filled carbon nanostructures were confirmed by powder X-ray diffraction, Raman, X-ray photoelectron spectroscopy, and high-resolution transmission electron microscopy images. Electrochemical tests demonstrated that the as-synthesized hybrid nanostructures exhibited outstanding electrocatalytic performance toward dopamine oxidation, with a high sensitivity of 19.62 μA μM-1 cm-2, low detection limit, broad linear …
Challenges And Opportunities In Electrification Of Adsorptive Separation Processes, Abdullah Al Moinee, Ali A. Rownaghi, Fateme Rezaei
Challenges And Opportunities In Electrification Of Adsorptive Separation Processes, Abdullah Al Moinee, Ali A. Rownaghi, Fateme Rezaei
Chemical and Biochemical Engineering Faculty Research & Creative Works
A global energy transition from fossil-based to renewable-based systems requires advancements in various energy sectors. Current chemical separation processes are quite energy-intensive and require significant advancement to make this transition happen. In the energy transition era, reducing the dependency of separation processes on fossil-based thermal energy seems inevitable for transitioning smoothly and meeting the stringent timelines. In particular, adsorption-based separation processes have the potential to be fully electrified through innovative strategies in developing stimuli-responsive adsorbents and swing processes. In this review, we discuss the recent efforts in electrification of adsorption processes and provide an overview of emerging materials and processes. …
Pd-Modified Cuo-Zno-Al2o3 Catalysts Via Mixed-Phases-Containing Precursor For Methanol Synthesis From Co2 Hydrogenation Under Mild Conditions, Xiao Fan, Kaiying Wang, Xiaoqing He, Shiguang Li, Miao Yu, Xinhua Liang
Pd-Modified Cuo-Zno-Al2o3 Catalysts Via Mixed-Phases-Containing Precursor For Methanol Synthesis From Co2 Hydrogenation Under Mild Conditions, Xiao Fan, Kaiying Wang, Xiaoqing He, Shiguang Li, Miao Yu, Xinhua Liang
Chemical and Biochemical Engineering Faculty Research & Creative Works
A series of palladium-modified (Pd-modified) CuO-ZnO-Al2O3 (CZA) catalysts with various Pd loadings (0.3 wt% to 2.4 wt%) were prepared using the wetness impregnation method, on two CZA supports with different structures that are CZA-aged precursor composed of a mixture of zincian-malachite and hydrotalcite-like phases (CZA-zH), and CuO-ZnO-Al2O3 metal oxide nanoparticles (CZA-MO). Enhancement on catalytic activity can be observed on both Pd-modified CZA catalysts in a temperature range of 180–240 °C for methanol synthesis via CO2 hydrogenation. Pd/CZA-zH catalysts exhibited a more efficient and stable production of methanol at a relatively low reaction temperature of 180 °C for 100 hrs. of …
Advancement In Heavy Oil Upgrading And Sustainable Exploration Emerging Technologies, Youssef Yatimi, Jihane Mendil, Meena Marafi, Ahmed Alalou, Muthanna H. Al-Dahhan
Advancement In Heavy Oil Upgrading And Sustainable Exploration Emerging Technologies, Youssef Yatimi, Jihane Mendil, Meena Marafi, Ahmed Alalou, Muthanna H. Al-Dahhan
Chemical and Biochemical Engineering Faculty Research & Creative Works
Upgrading heavy oil is a subject of high importance for fossil fuel industry due to the rapid depletion of light oil reservoirs and the consequent increased demand for upgrading heavy oil. In this review, the advancement made in heavy oil upgrading and the proposed sustainable emerging technologies dedicated to heavy oil processing have been discussed in a comprehensive and informative manner with consideration to the encountered associated with properties of heavy oil including its significant content of undesirable large molecular weight hydrocarbons, its high viscosity, and its elevated impurity level. The shortcomings of conventional crude oil upgrading technologies are outlined, …
Applications Of Plastics In The Automotive Industry: Current Trends And Future Perspectives, Hossein Abedsoltan
Applications Of Plastics In The Automotive Industry: Current Trends And Future Perspectives, Hossein Abedsoltan
Chemical and Biochemical Engineering Faculty Research & Creative Works
Plastics have transformed the automotive industry, contributing substantially to automobile design, weight reduction, fuel efficiency, safety, and sustainability. This review paper examines the applications of plastics in the automotive sector, evaluates the present trends, and describes the future plastic consumption possibilities, emphasizing emerging technology and sustainable practices. The paper delineates how plastics have become an essential component of automotive innovation and illustrates the possibilities for additional breakthroughs in this dynamic industry. Highlights: Advances in plastics, bioplastics, and smart materials in the auto industry. Plastic role in design, safety, and sustainability in the auto industry. Recycling and the circular economy of …
Physio-Chemical Modifications To Re-Engineer Small Extracellular Vesicles For Targeted Anticancer Therapeutics Delivery And Imaging, Rahmat Asfiya, Lei Xu, Anjugam Paramanantham, Kuanysh Kabytaev, Anna Chernatynskaya, Grace Mccully, Hu Yang, Akhil Srivastava
Physio-Chemical Modifications To Re-Engineer Small Extracellular Vesicles For Targeted Anticancer Therapeutics Delivery And Imaging, Rahmat Asfiya, Lei Xu, Anjugam Paramanantham, Kuanysh Kabytaev, Anna Chernatynskaya, Grace Mccully, Hu Yang, Akhil Srivastava
Chemical and Biochemical Engineering Faculty Research & Creative Works
Cancer theranostics developed through nanoengineering applications are essential for targeted oncologic interventions in the new era of personalized and precision medicine. Recently, small extracellular vesicles (sEVs) have emerged as an attractive nanoengineering platform for tumor-directed anticancer therapeutic delivery and imaging of malignant tumors. These natural nanoparticles have multiple advantages over synthetic nanoparticle-based delivery systems, such as intrinsic targeting ability, less immunogenicity, and a prolonged circulation time. Since the inception of sEVs as a viable replacement for liposomes (synthetic nanoparticles) as a drug delivery vehicle, many studies have attempted to further the therapeutic efficacy of sEVs. This article discusses engineering strategies …
Rab7 Deficiency Impairs Pulmonary Artery Endothelial Function And Promotes Pulmonary Hypertension, Bryce Piper, Srimathi Bogamuwa, Tanvir Hossain, Daniela Farkas, Lorena Rosas, Adam C. Green, Geoffrey Newcomb, Nuo Sun, Jose A. Ovando-Ricardez, Jeffrey C. Horowitz, Aneel R. Bhagwani, Hu Yang, Tatiana V. Kudryashova, Mauricio Rojas
Rab7 Deficiency Impairs Pulmonary Artery Endothelial Function And Promotes Pulmonary Hypertension, Bryce Piper, Srimathi Bogamuwa, Tanvir Hossain, Daniela Farkas, Lorena Rosas, Adam C. Green, Geoffrey Newcomb, Nuo Sun, Jose A. Ovando-Ricardez, Jeffrey C. Horowitz, Aneel R. Bhagwani, Hu Yang, Tatiana V. Kudryashova, Mauricio Rojas
Chemical and Biochemical Engineering Faculty Research & Creative Works
Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial dysfunction plays a central role in the development and progression of PAH, yet the underlying mechanisms are incompletely understood. The endosome-lysosome system is important to maintain cellular health, and the small GTPase RAB7 regulates many functions of this system. Here, we explored the role of RAB7 in endothelial cell (EC) function and lung vascular homeostasis. We found reduced expression of RAB7 in ECs from patients with PAH. Endothelial haploinsufficiency of RAB7 caused spontaneous pulmonary hypertension (PH) in mice. Silencing of RAB7 in ECs induced broad …
Estimation Of Co2 Absorption By A Hybrid Aqueous Solution Of Amino Acid Salt With Amine, Farid Amirkhani, Amir Dashti, Hossein Abedsoltan, Amir H. Mohammadi
Estimation Of Co2 Absorption By A Hybrid Aqueous Solution Of Amino Acid Salt With Amine, Farid Amirkhani, Amir Dashti, Hossein Abedsoltan, Amir H. Mohammadi
Chemical and Biochemical Engineering Faculty Research & Creative Works
Four developed machine learning algorithms are proposed to prognosticate the CO2 solubility in amino acid salt solutions, blended with amine solutions as additives, in broad ranges of temperature and pressure. From literature 375 experimental data points for CO2 solubility were collected. The results from the applied algorithms indicated that the CO2 solubility is estimated acceptably close to the experimental values. In the best case, the developed network estimates CO2 solubility in the stated solutions with an average relative deviation of 6.53 % and a correlation coefficient of 0.9892.
Reactive Capture And Conversion Of Co2 Into Hydrogen Over Bifunctional Structured Ce1-Xcoxnio3/Ca Perovskite-Type Oxide Monoliths, Khaled Baamran, Shane Lawson, Ali A. Rownaghi, Fateme Rezaei
Reactive Capture And Conversion Of Co2 Into Hydrogen Over Bifunctional Structured Ce1-Xcoxnio3/Ca Perovskite-Type Oxide Monoliths, Khaled Baamran, Shane Lawson, Ali A. Rownaghi, Fateme Rezaei
Chemical and Biochemical Engineering Faculty Research & Creative Works
Carbon capture, utilization, and storage (CCUS) technologies are pivotal for transitioning to a net-zero economy by 2050. In particular, conversion of captured CO2 to marketable chemicals and fuels appears to be a sustainable approach to not only curb greenhouse emissions but also transform wastes like CO2 into useful products through storage of renewable energy in chemical bonds. Bifunctional materials (BFMs) composed of adsorbents and catalysts have shown promise in reactive capture and conversion of CO2 at high temperatures. In this study, we extend the application of 3D printing technology to formulate a novel set of BFMs composed …
Retraction Notice To “High Density Conductive Lifepo4 Cathode With Enhanced High-Rate And High Temperature Performance” [Mater. Chem. Phys. 232 (2019) 367–373, (S0254058419304110), (10.1016/J.Matchemphys.2019.05.014)], David Seung-Hyun Lee, Won Bin Im, Xinhua Liang
Retraction Notice To “High Density Conductive Lifepo4 Cathode With Enhanced High-Rate And High Temperature Performance” [Mater. Chem. Phys. 232 (2019) 367–373, (S0254058419304110), (10.1016/J.Matchemphys.2019.05.014)], David Seung-Hyun Lee, Won Bin Im, Xinhua Liang
Chemical and Biochemical Engineering Faculty Research & Creative Works
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. The Editor-in-Chief found that the corresponding author of this article submitted the manuscript to the journal without the consent of the two individuals named as "co-authors", using invented email addresses to impersonate them. In addition, based on the raw materials presented to the journal by the second co-author and the Editor-in-Chief's own investigation, the Editor-in-Chief believes that some results in the paper are fabricated. Based on these two findings, the Editor-in-Chief has decided to retract the …
Flow Regimes In Bubble Columns With And Without Internals: A Review, Ayat N. Mahmood, Amer A. Abdulrahman, Laith S. Sabri, Abbas J. Sultan, Hasan Shakir Majdi, Muthanna H. Al-Dahhan
Flow Regimes In Bubble Columns With And Without Internals: A Review, Ayat N. Mahmood, Amer A. Abdulrahman, Laith S. Sabri, Abbas J. Sultan, Hasan Shakir Majdi, Muthanna H. Al-Dahhan
Chemical and Biochemical Engineering Faculty Research & Creative Works
Hydrodynamics characterization in terms of flow regime behavior is a crucial task to enhance the design of bubble column reactors and scaling up related methodologies. This review presents recent studies on the typical flow regimes established in bubble columns. Some effort is also provided to introduce relevant definitions pertaining to this field, namely, that of "void fraction" and related (local, chordal, cross-sectional and volumetric) variants. Experimental studies involving different parameters that affect design and operating conditions are also discussed in detail. In the second part of the review, the attention is shifted to cases with internals of various types (perforated …
Thermal Decomposition And Kinetic Parameters Of Three Biomass Feedstocks For The Performance Of The Gasification Process Using A Thermogravimetric Analyzer, Rania Almusafir, Joseph D. Smith
Thermal Decomposition And Kinetic Parameters Of Three Biomass Feedstocks For The Performance Of The Gasification Process Using A Thermogravimetric Analyzer, Rania Almusafir, Joseph D. Smith
Chemical and Biochemical Engineering Faculty Research & Creative Works
Thermogravimetric analysis (TGA) is a powerful technique and useful method for characterizing biomass as a non-conventional fuel. A TGA apparatus has been utilized to experimentally investigate the impact of biomass feedstock diversity on the performance of the gasification of hardwood (HW), softwood (SW) pellets, and refuse-derived fuel (RDF) materials. The solid conversion rate and the volatile species formation rate have been estimated to quantify the rates of devolatilization for each material. In addition, the combustion kinetic characteristics of the three biomass feedstocks were investigated using TGA at different heating rates, and a thermal kinetic analysis was conducted to describe the …
Gas-Phase Adsorption Of Dimethyl Methylphosphonate Over Ce(Oh)4@Pim-1 Composites Prepared Via Matrix Incorporation And Surface Coating Methods, Sukanta K. Mondal, Peter O. Aina, Ali A. Rownaghi, Fateme Rezaei
Gas-Phase Adsorption Of Dimethyl Methylphosphonate Over Ce(Oh)4@Pim-1 Composites Prepared Via Matrix Incorporation And Surface Coating Methods, Sukanta K. Mondal, Peter O. Aina, Ali A. Rownaghi, Fateme Rezaei
Chemical and Biochemical Engineering Faculty Research & Creative Works
This Study Investigated the Potential of Polymer of Intrinsic Microporosity (PIM-1) and Ce(OH)4@PIM-1 Composites for Adsorption of the Nerve Agent Simulant, Dimethyl Methylphosphonate (DMMP). through Experimental Investigations It Was Demonstrated that These Composite Adsorbents Exhibit Excellent Gas-Phase DMMP Adsorption Performance, with High Uptake Capacities and Relatively Fast Kinetics. This Study Further Examined the Effect of Two Composite's Preparation Methods, Namely Matrix Incorporation and Surface Coating, on the DMMP Adsorption Performance of Ce(OH)4@PIM-1. the Results Revealed that Coating of Ce(OH)4 on the PIM-1 Surface Gives Rise to Faster Adsorption Kinetics Than its Incorporation into the Polymer Matrix at Fixed 30 Wt …
Liposomes-Encapsulating Double-Stranded Nucleic Acid (Poly I:C) For Head And Neck Cancer Treatment, Vidit Singh, Anna Chernatynskaya, Lin Qi, Hsin Yin Chuang, Tristan Cole, Vimalin Mani Jeyalatha, Lavanya Bhargava, W. Andrew Yeudall, Laszlo Farkas, Hu Yang
Liposomes-Encapsulating Double-Stranded Nucleic Acid (Poly I:C) For Head And Neck Cancer Treatment, Vidit Singh, Anna Chernatynskaya, Lin Qi, Hsin Yin Chuang, Tristan Cole, Vimalin Mani Jeyalatha, Lavanya Bhargava, W. Andrew Yeudall, Laszlo Farkas, Hu Yang
Chemical and Biochemical Engineering Faculty Research & Creative Works
Polyriboinosinic acid-polyribocytidylic acid (Poly I:C) serves as a synthetic mimic of viral double-stranded dsRNA, capable of inducing apoptosis in numerous cancer cells. Despite its potential, therapeutic benefits, the application of Poly I:C has been hindered by concerns regarding toxicity, stability, enzymatic degradation, and undue immune stimulation, leading to autoimmune disorders. To address these challenges, encapsulation of antitumor drugs within delivery systems such as cationic liposomes is often employed to enhance their efficacy while minimizing dosages. In this study, we investigated the potential of cationic liposomes to deliver Poly I:C into the Head and Neck 12 (HN12) cell line to induce …
Novel Modified Polyethersulfone High Temperature And Low Humidity Fuel Cell Membrane: Experimental And Simulation Study, Mohammed K. Al Mesfer, Muthanna H. Al-Dahhan, Mohd Danish, Mumtaj Shah
Novel Modified Polyethersulfone High Temperature And Low Humidity Fuel Cell Membrane: Experimental And Simulation Study, Mohammed K. Al Mesfer, Muthanna H. Al-Dahhan, Mohd Danish, Mumtaj Shah
Chemical and Biochemical Engineering Faculty Research & Creative Works
The Present Study Focuses on Synthesizing a High-Temperature Stable Membrane Working under Low Relative Humidity (RH) by Aminating the Traditional Polyethersulfone Polymer with Aniline for Fuel Cell Applications. a Condensed-Phase Optimized Molecular Potentials for Atomistic Simulation Studies Force Field-Based Molecular Dynamics Simulation Was Used to Explore the Microscopic Properties and Transport of Water and Hydronium (H3O+) Ions Across the Electrolyte at Varied Temperatures and RHs. COMSOL Calculates Oxygen and Hydrogen Concentrations after Examining the Polymer–ion Interaction with the Radial Distribution Function (RDF). the High H3O+ Diffusion Coefficient of the Aniline-Treated Membrane Shows the Benefit of the Modification. the RDF Confirmed …
Robust Triso-Fueled Pebble Identification By Digit Recognition, Roshan Kenia, Jihane Mendil, Ahmed Jasim, Muthanna Al-Dahhan, Zhaozheng Yin
Robust Triso-Fueled Pebble Identification By Digit Recognition, Roshan Kenia, Jihane Mendil, Ahmed Jasim, Muthanna Al-Dahhan, Zhaozheng Yin
Chemical and Biochemical Engineering Faculty Research & Creative Works
Nuclear Power Plays a Vital Role in Providing Reliable and Clean Energy to Fulfill Increasing Demands in Electricity Worldwide. It Continues to Be an Essential Source of National Power Supply as Growing Concerns About Fossil Fuel Depletion, Global Warming, and Emissions Require Utilizing Sustainable Energy Sources. One Area Contributing to the Growth of Nuclear Power is the Development of Reactors that Have Enhanced Protection and Security, Thermal Efficiency, and Design. Reactor Efficiency Can Be Studied by the Burnup that Occurs When a TRISO-Fueled Pebble is Inserted into the Nuclear Core and Subsequently Removed. the Levels of Burnup Are Measured based …