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Full-Text Articles in Chemical Engineering
Functionalization Of Iron Oxide Nanoparticles And The Impact On Surface Reactive Oxygen Species Generation For Potential Biomedical And Environmental Applications, Trang Mai
Theses and Dissertations--Chemical and Materials Engineering
Iron oxide nanoparticles (IONPs) have been widely studied for a variety of applications, from biomedical applications (e.g., cell separation, drug delivery, contrast agent for magnetic resonance imaging and magnetically mediated energy delivery for cancer treatment) to environmental remediations (e.g., heavy metal removal and organic pollutants degradation). It has been demonstrated that IONPs can induce the production of reactive oxygen species (ROS) via Fenton/Haber-Weiss reactions which has been shown to be one of the key underlying mechanisms of nanoparticles toxicity. This inherent toxicity of nanoparticles has been shown to enhance the efficacy of traditional cancer therapies such as chemotherapy and radiation. …
Development Of Magnetic Nanocomposite Materials As Reusable Adsorbents For Chlorinated Organics In Contaminated Water, Angela Gutierrez
Development Of Magnetic Nanocomposite Materials As Reusable Adsorbents For Chlorinated Organics In Contaminated Water, Angela Gutierrez
Theses and Dissertations--Chemical and Materials Engineering
The constant growth in population worldwide over the past decades continues to put forward the need to provide access to safe, clean water to meet human needs. There is a need for cost-effective technologies for water and wastewater treatment that can meet the global demands and the rigorous water quality standards and at the same maximizing pollutant efficiency removal. Current remediation technologies have failed in keeping up with these factors without becoming cost-prohibitive. Nanotechnology has recently been sought as a promising option to achieve these goals. The use of iron oxide magnetic nanoparticles as nanoadsorbents has led to a new …
Surface Functionalized Magnetic Nanoparticles For Cancer Therapy Applications, Robert J. Wydra
Surface Functionalized Magnetic Nanoparticles For Cancer Therapy Applications, Robert J. Wydra
Theses and Dissertations--Chemical and Materials Engineering
Despite recent advances, cancer remains the second leading cause of deaths in the United States. Magnetic nanoparticles have found various applications in cancer research as drug delivery platforms, enhanced contrast agents for improved diagnostic imaging, and the delivery of thermal energy as standalone therapy. Iron oxide nanoparticles absorb the energy from an alternating magnetic field and convert it into heat through Brownian and Neel relaxations. To better utilize magnetic nanoparticles for cancer therapy, surface functionalization is essential for such factors as decreasing cytotoxicity of healthy tissue, extending circulation time, specific targeting of cancer cells, and manage the controlled delivery of …