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Full-Text Articles in Chemical Engineering

Apple Pomace Consumption Favorably Alters Hepatic Lipid Metabolism In Young Female Sprague-Dawley Rats Fed A Western Diet, Roy Chris Skinner, Derek C. Warren, Soofie N. Lateef, Vagner A. Benedito, Janet C. Tou Jan 2018

Apple Pomace Consumption Favorably Alters Hepatic Lipid Metabolism In Young Female Sprague-Dawley Rats Fed A Western Diet, Roy Chris Skinner, Derek C. Warren, Soofie N. Lateef, Vagner A. Benedito, Janet C. Tou

Faculty & Staff Scholarship

Apple pomace, which is a waste byproduct of processing, is rich in several nutrients, particularly dietary fiber, indicating potential benefits for diseases that are attributed to poor diets, such as non-alcoholic fatty liver disease (NAFLD). NAFLD affects over 25% of United States population and is increasing in children. Increasing fruit consumption can influence NAFLD. The study objective was to replace calories in standard or Western diets with apple pomace to determine the effects on genes regulating hepatic lipid metabolism and on risk of NAFLD. Female Sprague-Dawley rats were randomly assigned (n = 8 rats/group) to isocaloric diets of AIN-93G and …


Metabolic Comparison Of Wild-Type And Transgenic Synechocystis Pcc 6803 Cyanobacteria, Ian A. Mcluckey, John A. Morgan, Joel Yu King Hing Aug 2017

Metabolic Comparison Of Wild-Type And Transgenic Synechocystis Pcc 6803 Cyanobacteria, Ian A. Mcluckey, John A. Morgan, Joel Yu King Hing

The Summer Undergraduate Research Fellowship (SURF) Symposium

The Calvin-Benson (CBB) cycle is an essential part of nature. This phenomenon allows carbon molecules in carbon dioxide from the atmosphere to be converted into useful energy in the form of sugars. Cyanobacteria are single-celled organisms capable of utilizing energy from sunlight to drive this cycle and are also readily engineered. In hopes of improving this cycle, we compared a wild-type version of the Synechocystis PCC6803 cyanobacteria to an engineered version overexpressing the enzyme FBA (fructose-biphosphate aldolase), called 70 glpX, to deduce how the overexpressing strain is able to be more photosynthetically efficient. To do this, comparative metabolomics were done …