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Full-Text Articles in Bioimaging and Biomedical Optics

K-Wire Differentiation, Oluwadamilola Oluwadara, Lillian Maresco, Eunjung Lee, Michelle De Leon Jun 2021

K-Wire Differentiation, Oluwadamilola Oluwadara, Lillian Maresco, Eunjung Lee, Michelle De Leon

Honors Theses

Kirschner Pins, known as K-wires, are smooth sharp stainless steel pins used in the field of orthopedics to stabilize bone fracture fragments in their correct position until they have fully healed. K-wires are most commonly used for comminuted metaphyseal fractures of the long bones, and fractures of smaller bones such as the phalanges. The wires are inserted into bone via a drill and the ends of the wire are bent and left outside of the body for easy removal once the bone has healed. The surgeon uses x-ray images to guide K-wire insertion, ensure proper internal alignment, and determine if …


Preclinical Development Of Single Walled Carbon Nanotube-Based Optical Biosensors, Eric M. Hofferber Apr 2021

Preclinical Development Of Single Walled Carbon Nanotube-Based Optical Biosensors, Eric M. Hofferber

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

High resolution, long-term monitoring of key biological analytes would improve patient outcomes by providing earlier detection of disease states and improved efficacy of treatment. One class of biosensors that have gained much attention in recent years are optical biosensors. Optical probes are attractive biosensors due to their noninvasive nature of detection, as certain light can pass through tissue, water, and blood. Single walled carbon nanotubes (SWNT) are a specific type of optical biosensor that fluoresce in the near infrared range of the electromagnetic spectrum and offer unparalleled spatial and temporal resolution. SWNT have been applied as biosensors in vitro, …


Development Of Light Actuated Chemical Delivery Platform On A 2-D Array Of Micropore Structure, Hojjat Rostami Azmand, Hojjat Rostami Azmand Jan 2021

Development Of Light Actuated Chemical Delivery Platform On A 2-D Array Of Micropore Structure, Hojjat Rostami Azmand, Hojjat Rostami Azmand

Dissertations and Theses

Localized chemical delivery plays an essential role in the fundamental information transfers within biological systems. Thus, the ability to mimic the natural chemical signal modulation would provide significant contributions to understand the functional signaling pathway of biological cells and develop new prosthetic devices for neurological disorders. In this paper, we demonstrate a light-controlled hydrogel platform that can be used for localized chemical delivery in a high spatial resolution. By utilizing the photothermal behavior of graphene-hydrogel composites confined within micron-sized fluidic channels, patterned light illumination creates the parallel and independent actuation of chemical release in a group of fluidic ports. The …