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Full-Text Articles in Biomedical Engineering and Bioengineering

Ultrasound-Based Tissue Characterization And Classification Of Fatty Liver Disease: A Screening And Diagnostic Paradigm Feb 2015

Ultrasound-Based Tissue Characterization And Classification Of Fatty Liver Disease: A Screening And Diagnostic Paradigm

Faculty of Engineering University of Malaya

Fatty Liver Disease (FLD) is a progressively prevalent disease that is present in about 15% of the world population. Normally benign and reversible if detected at an early stage, FLD, if left undetected and untreated, can progress to an irreversible advanced liver disease, such as fibrosis, cirrhosis, liver cancer and liver failure, which can cause death. Ultrasound (US) is the most widely used modality to detect FLD. However, the accuracy of US-based diagnosis depends on both the training and expertise of the radiologist. US-based Computer Aided Diagnosis (CAD) techniques for FLD detection can improve accuracy, speed and objectiveness of the …


Development Of A Cell Morphological Analysis Tool To Evaluate The Ultrasound Vibrational Effects On Cell Adhesion, Joseph M. Smith Jan 2015

Development Of A Cell Morphological Analysis Tool To Evaluate The Ultrasound Vibrational Effects On Cell Adhesion, Joseph M. Smith

Dissertations, Master's Theses and Master's Reports - Open

Fibroblast encapsulation is a stage of the wound healing process in which the implanted device is separated from the biological environment due to the formation of fibrotic tissue. Uncontrolled adhesion of fibroblasts, called fibrosis, has the ability to inhibit an implanted device’s functionality over its lifetime. Over time, fibroblasts have been shown to cause loosening and failure of bone-anchor implants which could include the possibility of harming the patient. The encapsulating process could also hinder the sensitivity of implanted biosensors operating in the body for continuous monitoring. Unfortunately, the antifouling surfaces which are commonly used on implanted devices to control …