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Full-Text Articles in Biomedical Engineering and Bioengineering

3d Thoracoscopic Ultrasound Volume Measurement Validation In An Ex Vivo And In Vivo Porcine Model Of Lung Tumours, V. Hornblower, E. Yu, A. Fenster, J. Battista, R. Malthaner Jul 2015

3d Thoracoscopic Ultrasound Volume Measurement Validation In An Ex Vivo And In Vivo Porcine Model Of Lung Tumours, V. Hornblower, E. Yu, A. Fenster, J. Battista, R. Malthaner

Richard A. Malthaner

The purpose of this study was to validate the accuracy and reliability of volume measurements obtained using three-dimensional (3D) thoracoscopic ultrasound (US) imaging. Artificial "tumours" were created by injecting a liquid agar mixture into spherical moulds of known volume. Once solidified, the "tumours" were implanted into the lung tissue in both a porcine lung sample ex vivo and a surgical porcine model in vivo. 3D US images were created by mechanically rotating the thoracoscopic ultrasound probe about its long axis while the transducer was maintained in close contact with the tissue. Volume measurements were made by one observer using the …


3d Thoracoscopic Ultrasound Volume Measurement Validation In An Ex Vivo And In Vivo Porcine Model Of Lung Tumours, V. Hornblower, E. Yu, A. Fenster, J. Battista, R. Malthaner Jul 2015

3d Thoracoscopic Ultrasound Volume Measurement Validation In An Ex Vivo And In Vivo Porcine Model Of Lung Tumours, V. Hornblower, E. Yu, A. Fenster, J. Battista, R. Malthaner

Richard A. Malthaner

The purpose of this study was to validate the accuracy and reliability of volume measurements obtained using three-dimensional (3D) thoracoscopic ultrasound (US) imaging. Artificial "tumours" were created by injecting a liquid agar mixture into spherical moulds of known volume. Once solidified, the "tumours" were implanted into the lung tissue in both a porcine lung sample ex vivo and a surgical porcine model in vivo. 3D US images were created by mechanically rotating the thoracoscopic ultrasound probe about its long axis while the transducer was maintained in close contact with the tissue. Volume measurements were made by one observer using the …


A Pneumatically Actuated Manipulandum For Neuromotor Control Research, Aaron J Suminski, Kristina Ropella, Robert Scheidt Mar 2015

A Pneumatically Actuated Manipulandum For Neuromotor Control Research, Aaron J Suminski, Kristina Ropella, Robert Scheidt

Robert Scheidt

Functional magnetic resonance imaging (fMRI) techniques have great potential for identifying which neural structures are involved in the control of goal-directed reaching movements. However, fMRI techniques alone are not capable of probing the neural mechanisms involved in acquisition of novel motor behaviors because such studies require that the moving limb be perturbed in a controlled fashion. We outline a plan to design and develop a non-metallic, pneumatically actuated tool that, along with systems identification techniques and functional magnetic resonance imaging (fMRI), will characterize and quantify how the human central nervous system uses sensory information during practice-based motor learning.


A Low-Field P-31 Nmr Spectrometer To Measure Bone Mineral In The Human Wrist, Joseph Battocletti, Thomas Meyers, Robert Scheidt Mar 2015

A Low-Field P-31 Nmr Spectrometer To Measure Bone Mineral In The Human Wrist, Joseph Battocletti, Thomas Meyers, Robert Scheidt

Robert Scheidt

Nuclear magnetic resonance phosphorus spectroscopy (NMRS) is a method of measuring the mineral content of bone as a diagnostic tool for osteoporosis. A description is given of the design and construction of a low-field spectrometer for the human wrist. It uses a small-size permanent magnet of neodymium-iron-boron. The questions of whether a low-field spectrometer is sensitive enough to measure the phosphorus mineral content of bone and to what extent the phosphorus in soft tissue affects the measurement of bone mass are discussed