Biomedical Engineering and Bioengineering Commons^™

Rhea Breast Pump: Implementation Of Biomimicry Technology, Harper Daniels, Leanne James, Laini Reynolds, Courtney Rowe, Julia Yaklich

Interdisciplinary Design Senior Theses

Rhea Breast Pump is an innovative breast pump that implements biomimicry informed technology for a more efficient and comfortable breastfeeding experience. Our design implements a tongue actuator in conjunction with vacuum to mimic the suckling motion of a baby’s mouth, a heating element for pain alleviation, and a soft flange to maximize comfort. The development of this device is motivated by the goal of empowering women, specifically nursing mothers, to maintain their independence and individuality while raising a family. Our team, consisting of all female engineers, strongly believes in and supports the notion that women can and should have the …

3-D Silk Fibroin Porous Particles Created By The Ouzo Effect For Biomedical Applications, Ashley Nicole Lamb

UNLV Theses, Dissertations, Professional Papers, and Capstones

Due to its high biocompatibility and biodegradability, silk fibroin – produced from

Bombyx mori (B. mori) cocoons – has been at the forefront of research for many

biomedical application formats: hydrogels, films, microspheres, and porous

sponges/scaffolding, to name a few. For drug delivery, in particular, porous particles are

desirable for their large surface area, uniform and tunable pore structure, and high

porosity. This thesis focuses on the fabrication of porous particles from silk fibroin by the

very interesting Ouzo effect. The Ouzo effect, so named because of the Greek

beverage ouzo, describes the phenomenon of an ethanol + anethole oil …

Human-Centered Electric Prosthetic (Help) Hand, Jamie Ferris, Shiyin Lim, Michael Mehta, Evan Misuraca

Interdisciplinary Design Senior Theses

Through a partnership with Indian non-profit Bhagwan Mahaveer Viklang Sahayata Samiti, we designed a functional, robust, and and low cost electrically powered prosthetic hand that communicates with unilateral, transradial, urban Indian amputees through a biointerface. The device uses compliant tendon actuation, a small linear servo, and a wearable garment outfitted with flex sensors to produce a device that, once placed inside a prosthetic glove, is anthropomorphic in both look and feel. The prosthesis was developed such that future groups can design for manufacturing and distribution in India.

Biodegradable And Biocompatible Silk Fibroin For Optical Applications, Corey Bryce Malinowski

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study presents nanopatterned silk fibroin films that were fabricated using soft lithography and nanoimprinting to replicate patterns from diffraction gratings. These film’s optics were analyzed based on their light scattering potential as well as their transmittance and transmission haze using a laser light, spectrometer, and UV-Vis spectrophotometer, respectively. The patterned fibroin films all displayed similar light scattering patterns to their master patterns with some transmission haze. When using the spectrometer to measure samples, those made without any nanostructure displayed transmission of 90% and over, while those with patterns depended on the structure used. The denser a structure, like the …

Enhancing Mobility And Independence Of Wheelchair Users, Briar Blake, Paul Nauleau

Interdisciplinary Design Senior Theses

Conditions as simple as a leg fracture or more severe impairments such as paralysis and stroke may confine a person to a wheelchair. Wheelchairs help people with limited mobility transport themselves to different locations, but do not help the person leave the wheelchair. Users would need to do this to enter a car, use the restroom, take a shower, and sit at a table comfortably with family. The following design is a wheelchair attachment that serves to provide the user with increased mobility and independence. Wheelchair users struggle to get into and out of their chairs due to the unassisted …

Powering A Biosensor Using Wearable Thermoelectric Technology, Anneliese Bals, Noah Barnes, Rafael Bravo, Nicolas Garcia, Joseph O'Bryan, Dylan Santana

Interdisciplinary Design Senior Theses

Wearable medical devices such as insulin pumps, glucose monitors, hearing aids, and electrocardiograms provide necessary medical aid and monitoring to millions of users worldwide. These battery powered devices require battery replacement and frequent charging that reduces the freedom and peace of mind of users. Additionally, the significant portion of the world without access to electricity is unable to use these medical devices as they have no means to power them constantly. Wearable thermoelectric power generation aims to charge these medical device batteries without a need for grid power.

Our team has developing a wristband prototype that uses body heat, ambient …

Microfluidic E. Coli Detection, Kyle Pietrzyk, Scott Fukuoka, Andres Maldonado-Liu, Andy Ly

Interdisciplinary Design Senior Theses

In both developed and developing countries, there is a need for a fast diagnostic system to detect pathogens within a fluid sample. In developing a microfluidic platform, which utilizes a microfluidic chip and an optical detection method, doors may be opened for new methods of determining pathogen concentration in fluid. Most biological reactions are not instantaneous. A flow-controlling mechanism with no power requirement may be implemented in the microfluidic platform. As a proof-of-concept, our device uses a microfluidic chip, smartphone, and microlens to detect E. coli concentrations in water. The detection method is based on the latex agglutination assay which …

Characterising 3d Soft Tissue Features On Joint Surfaces, Colm O'Kane

Conference Papers

A crucial aspect of orthopaedic implant design is the prediction of surgical outcomes when the shape of a bone is necessarily altered by the addition of the implant. Matching native kinematics as closely as possible is generally considered a core aim of joint replacement surgery. The overall hypothesis behind this research is that soft tissue geometry, including cartilage thickness distribution and ligament attachment sites, influences kinematics in the knee joint. In order to enable investigation of possible links between geometry and kinematics, the ability to characterise the shape variation of the soft tissue relative to the underlying bony geometry must …