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Biomedical Engineering and Bioengineering Commons™
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Articles 1 - 12 of 12
Full-Text Articles in Biomedical Engineering and Bioengineering
Low-Intensity Vibration Restores Nuclear Yap Levels And Acute Yap Nuclear Shuttling In Mesenchymal Stem Cells Subjected To Simulated Microgravity, Matthew Thompson, Kali Woods, Joshua Newberg, Julia Thom Oxford, Gunes Uzer
Low-Intensity Vibration Restores Nuclear Yap Levels And Acute Yap Nuclear Shuttling In Mesenchymal Stem Cells Subjected To Simulated Microgravity, Matthew Thompson, Kali Woods, Joshua Newberg, Julia Thom Oxford, Gunes Uzer
Mechanical and Biomedical Engineering Faculty Publications and Presentations
Reducing the musculoskeletal deterioration that astronauts experience in microgravity requires countermeasures that can improve the effectiveness of otherwise rigorous and time-expensive exercise regimens in space. The ability of low-intensity vibrations (LIV) to activate force-responsive signaling pathways in cells suggests LIV as a potential countermeasure to improve cell responsiveness to subsequent mechanical challenge. Mechanoresponse of mesenchymal stem cells (MSC), which maintain bone-making osteoblasts, is in part controlled by the “mechanotransducer” protein YAP (Yes-associated protein), which is shuttled into the nucleus in response to cyto-mechanical forces. Here, using YAP nuclear shuttling as a measurement outcome, we tested the effect of 72 h …
Annual Simulation Of Photovoltaic Retrofits Within Existing Parabolic Trough Concentrating Solar Powerplants, Nipun Goel, Hannah O'Hern, Matthew Orosz, Todd Otanicar
Annual Simulation Of Photovoltaic Retrofits Within Existing Parabolic Trough Concentrating Solar Powerplants, Nipun Goel, Hannah O'Hern, Matthew Orosz, Todd Otanicar
Mechanical and Biomedical Engineering Faculty Publications and Presentations
Solar power for electricity production comes from either photovoltaics or concentrating solar power plants. The former has seen rapid growth and expansion due to the rapid fall in global prices, while the latter has seen moderate growth due to ability to cheaply store thermal energy for later use. Hybridization, or combining photovoltaics with concentrating solar power represents a potential way for lowering cost while enabling long term storage. Over 5 GW of capacity exist worldwide using parabolic trough style technology for concentrating solar power which presents a unique option for optimization in the form of a photovoltaic retrofit. While it …
Emerging Gene-Editing Modalities For Osteoarthritis, Alekya S. Tanikella, Makenna J. Hardy, Stephanie M. Frahs, Aidan G. Cormier, Kalin D. Gibbons, Clare K. Fitzpatrick, Julia Thom Oxford
Emerging Gene-Editing Modalities For Osteoarthritis, Alekya S. Tanikella, Makenna J. Hardy, Stephanie M. Frahs, Aidan G. Cormier, Kalin D. Gibbons, Clare K. Fitzpatrick, Julia Thom Oxford
Mechanical and Biomedical Engineering Faculty Publications and Presentations
Osteoarthritis (OA) is a pathological degenerative condition of the joints that is widely prevalent worldwide, resulting in significant pain, disability, and impaired quality of life. The diverse etiology and pathogenesis of OA can explain the paucity of viable preventive and disease-modifying strategies to counter it. Advances in genome-editing techniques may improve disease-modifying solutions by addressing inherited predisposing risk factors and the activity of inflammatory modulators. Recent progress on technologies such as CRISPR/Cas9 and cell-based genome-editing therapies targeting the genetic and epigenetic alternations in OA offer promising avenues for early diagnosis and the development of personalized therapies. The purpose of this …
Revolutionizing The Mechanical Engineering Undergraduate Curriculum, Shelby Ann Mcneilly, Krishna Pakala, Donald Plumlee
Revolutionizing The Mechanical Engineering Undergraduate Curriculum, Shelby Ann Mcneilly, Krishna Pakala, Donald Plumlee
Mechanical and Biomedical Engineering Faculty Publications and Presentations
As the age of technological advancement and occupational opportunity continues to progress, companies must be constantly adjusting and transforming in order to accommodate industry demands. With these quickly developing requirements comes an expectation of employee experience and skill sets. For individuals seeking a career in mechanical engineering, moving forward with the tools necessary for success in this continuously evolving world begins with higher education. This paper is the first of a three-part series to report on the progress of Boise State University’s Mechanical and Biomedical Engineering Department’s mission to implement a revolutionized curriculum in their academic program. This paper will …
Faculty Perspectives On The Impact Of Virtual Office Hours In Engineering Courses, Brooke-Lynn Caprice Andrade, Krishna Pakala, Diana Bairaktarova, Douglas Hagemeier, Harish Subbaraman
Faculty Perspectives On The Impact Of Virtual Office Hours In Engineering Courses, Brooke-Lynn Caprice Andrade, Krishna Pakala, Diana Bairaktarova, Douglas Hagemeier, Harish Subbaraman
Mechanical and Biomedical Engineering Faculty Publications and Presentations
Instructor-student interaction is an important element of a course design, but office hours can be challenging to attend based on students’ commitments. They have time and space limitations that prevent students from getting the help they need and often garner poor attendance. Virtual office hours can address issues related to low attendance and provide a low stakes environment where unhindered learning can happen. Virtual office hours are flexible, yield productive interactions, and all enrolled students can participate. This study reports on three engineering instructors’ perspectives on the efficacy of virtual office hours compared to the traditional face-to-face interactions with the …
Heating Performance Analysis For Short-Term Energy Monitoring And Prediction Using Multi-Family Residential Energy Consumption Data, Sukjoon Oh, Chul Kim, Joonghyeok Heo, Sung Lok Do, Kee Han Kim
Heating Performance Analysis For Short-Term Energy Monitoring And Prediction Using Multi-Family Residential Energy Consumption Data, Sukjoon Oh, Chul Kim, Joonghyeok Heo, Sung Lok Do, Kee Han Kim
Mechanical and Biomedical Engineering Faculty Publications and Presentations
Many smart apartments and renovated residential buildings have installed Smart Meters (SMs), which collect interval data to accelerate more efficient energy management in multi-family residential buildings. SMs are widely used for electricity, but many utility companies have been working on systems for natural gas and water monitoring to be included in SMs. In this study, we analyze heating energy use data obtained from SMs for short-term monitoring and annual predictions using change-point models for the coefficient checking method. It was found that 9-month periods were required to search the best short-term heating energy monitoring periods when non-weather-related and weather-related heating …
Simulation Of Cu Precipitation In Fe-Cu Dilute Alloys With Cluster Mobility, Senlin Cui, Mahmood Mamivand, Dane Morgan
Simulation Of Cu Precipitation In Fe-Cu Dilute Alloys With Cluster Mobility, Senlin Cui, Mahmood Mamivand, Dane Morgan
Mechanical and Biomedical Engineering Faculty Publications and Presentations
Cu-rich precipitates formation is associated with the precipitation hardening of Fe-Cu based steels and the embrittlement of reactor pressure vessel steels under neutron irradiation. The accurate modeling of the time evolution of Cu-rich precipitates is therefore of fundamental importance for the design of Fe-Cu based steels and the prediction of the irradiation induced shift of the ductile to brittle transition temperature of reactor pressure vessels. This work applies cluster dynamics with mobile Cu monomers and clusters to model Cu precipitation in dilute Fe-Cu alloys at several temperatures. Optimized model parameters can be used to simulate the mean radius, number density, …
Concentrating Photovoltaic Retrofit For Existing Parabolic Trough Solar Collectors: Design, Experiments, And Levelized Cost Of Electricity, Todd P. Otanicar, Rhetta Wingert, Matthew Orosz, Clay Mcpheeters
Concentrating Photovoltaic Retrofit For Existing Parabolic Trough Solar Collectors: Design, Experiments, And Levelized Cost Of Electricity, Todd P. Otanicar, Rhetta Wingert, Matthew Orosz, Clay Mcpheeters
Mechanical and Biomedical Engineering Faculty Publications and Presentations
Photovoltaics and concentrating solar thermal power are two ways for generating electricity from sunlight, albeit through different methods. Parabolic trough style powerplants represent 3.6 GW of electricity production, but many of these plants are aging and being replaced with photovoltaics. An alternative option that could be employed to leverage the sunk capital cost associated with the primary optics would be the design of a pure photovoltaic retrofit working within the existing plant architecture. Here, a secondary optical concentrator is designed to use the existing primary optics of a parabolic trough type solar thermal powerplant. The design is a v-shaped secondary …
Computational Approach To Correcting Joint Instability In Patients With Recurrent Patellar Dislocation, Oliver Alvarez, Robert N. Steensen, Paul J. Rullkoetter, Clare K. Fitzpatrick
Computational Approach To Correcting Joint Instability In Patients With Recurrent Patellar Dislocation, Oliver Alvarez, Robert N. Steensen, Paul J. Rullkoetter, Clare K. Fitzpatrick
Mechanical and Biomedical Engineering Faculty Publications and Presentations
Patellar dislocation is a debilitating injury common in active adolescents and young adults. Conservative treatment after initial dislocation is often recommended, but almost half of these patients continue to suffer from recurrent dislocation. The objective of this study was to compare preoperative patellofemoral joint stability with stability after a series of simulated procedures, including restorative surgery to correct to pre-injury state, generic tibial tubercle osteotomy, patient-specific reconstructive surgery to correct anatomic abnormality, less invasive patient-specific surgery, and equivalent healthy controls. Three-dimensional, subject-specific finite element models of the patellofemoral joint were developed for 28 patients with recurrent patellar dislocation. A …
Review Of Living Learning Communities And Their Impact On First Year Engineering College Students, Samantha Schauer, Krishna Pakala, Kim M.B. Tucker
Review Of Living Learning Communities And Their Impact On First Year Engineering College Students, Samantha Schauer, Krishna Pakala, Kim M.B. Tucker
Mechanical and Biomedical Engineering Faculty Publications and Presentations
Traditionally, first-year college students do not have a community of like-minded peers with whom they are able to learn. Adding to first-year engineering college students’ (FYECS) struggles is the fact that many students do not have a mentor in their related field and are unable to start building their professional repertoire, network, and/or practical skills. Living Learning Communities (LLC) can offer a platform for postsecondary institutions to increase recruitment, engagement, and sense of belonging for students who live in an LLC. LLCs have been described in the literature as themed living and learning communities where students take a common course(s), …
A Mobile Learning Community In A Living Learning Community: Perceived Impact On Digital Fluency And Communication, Devshikha Bose, Krishna Pakala, Lana Grover
A Mobile Learning Community In A Living Learning Community: Perceived Impact On Digital Fluency And Communication, Devshikha Bose, Krishna Pakala, Lana Grover
Mechanical and Biomedical Engineering Faculty Publications and Presentations
Though mobile devices like smartphones, tablets, and tablet computers have an immense potential for improving student learning, there is little empirical research which reports ways in which students actually use these technologies for learning, especially in fields like Engineering. Based on a social-constructivist approach to learning, the purpose of this mixed methods study was to investigate student perceptions regarding changes in mobile device based digital fluency and communication, after participation in a Living Learning Community (LLC) based Mobile Learning Community. This study contributes to existing literature in the field in that it reports student perceptions of how mobile devices can …
Fuzzy Controller Algorithm For Automated Hvac Control, M. Chae, K. Kang, D. Koo, S. Oh, Jae Youl Chun
Fuzzy Controller Algorithm For Automated Hvac Control, M. Chae, K. Kang, D. Koo, S. Oh, Jae Youl Chun
Mechanical and Biomedical Engineering Faculty Publications and Presentations
This research presents the design framework of the artificial intelligent algorithm for an automated building management system. The AI system uses wireless sensor data or IoT (Internet of Things) and user's feedback together. The wireless sensors collect data such as temperature (indoor and outdoor), humidity, light, user occupancy of the facility, and Volatile Organic Compounds (VOC) which is known as the source of the Sick Building Syndrome (SBS) or New Building Syndrome because VOC are often found in new buildings or old buildings with new interior improvement and they can be controlled and reduced by appropriate ventilation efforts. The collected …