Biomedical Engineering and Bioengineering Commons^™

Developing Vascular Graft From Adipose-Derived Stem Cells, Ashley C. Apil

Research Opportunities for Engineering Undergraduates (ROEU) Program 2017-18

This project aims to differentiate adipose-derived stem cells into fibroblasts through the addition of platelet-derived growth factor (PDGF) into the culture media. Differentiation protocol will be optimized, then successful differentiation will be verified through PCR analysis. The ASC-fibroblasts will then be seeded into a ring construct as outlined by the protocol by Lam et al. The ring constructs will be tensile tested and analyzed through histology to characterize their strength and cellularity.