Biomedical Engineering and Bioengineering Commons^™

Quantification Of Local Hemodynamic Alterations Caused By Virtual Implantation Of Three Commercially Available Stents For The Treatment Of Aortic Coarctation, Sung Kwon, Jeffrey A. Feinstein, Ronak Jashwant Dholakia, John F. Ladisa

Biomedical Engineering Faculty Research and Publications

Patients with coarctation of the aorta (CoA) are prone to morbidity including atherosclerotic plaque that has been shown to correlate with altered wall shear stress (WSS) in the descending thoracic aorta (dAo). We created the first patient-specific computational fluid dynamics (CFD) model of a CoA patient treated by Palmaz stenting to date, and compared resulting WSS distributions to those from virtual implantation of Genesis XD and modified NuMED CP stents, also commonly used for CoA. CFD models were created from magnetic resonance imaging, fluoroscopy and blood pressure data. Simulations incorporated vessel deformation, downstream vascular resistance and compliance to match measured …