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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Measuring The Mechanical Properties Of Living Cells Using Atomic Force Microscopy, Nancy Burnham, Gawain Thomas, Terri Camesano, Qi Wen Jun 2013

Measuring The Mechanical Properties Of Living Cells Using Atomic Force Microscopy, Nancy Burnham, Gawain Thomas, Terri Camesano, Qi Wen

Nancy A. Burnham

Mechanical properties of cells and extracellular matrix (ECM) play important roles in many biological processes including stem cell differentiation, tumor formation, and wound healing. Changes in stiffness of cells and ECM are often signs of changes in cell physiology or diseases in tissues. Hence, cell stiffness is an index to evaluate the status of cell cultures. Among the multitude of methods applied to measure the stiffness of cells and tissues, micro-indentation using an Atomic Force Microscope (AFM) provides a way to reliably measure the stiffness of living cells. This method has been widely applied to characterize the micro-scale stiffness for …


Lipid Production By Scenedesmus Dimorphus: Comparison Of Extraction Techniques And Effect Of Sodium Nitrate Concentration, Bahareh Kanani Jan 2013

Lipid Production By Scenedesmus Dimorphus: Comparison Of Extraction Techniques And Effect Of Sodium Nitrate Concentration, Bahareh Kanani

ETD Archive

No abstract provided.


Moving Horizon Estimation With Dynamic Programming, Mohan Kumar Ramalingam Jan 2013

Moving Horizon Estimation With Dynamic Programming, Mohan Kumar Ramalingam

ETD Archive

Moving Horizon Estimation(MHE) is a optimization based strategy to state estimation. It involves computation of arrival cost, a penalty term, based on the MHE cost function. Minimization of this arrival cost is done through various methods. All these methods use nonlinear programming optimization technique which gives the estimate. The main idea of MHE revolves around minimizing the estimation cost function. The cost function is dependent on prediction error computation from data and arrival cost summarization. The major issue that hampers the MHE is choosing the arrival cost for ensuring stability of the overall estimation and computational time. In order to …