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Biomedical Engineering and Bioengineering Commons

Open Access. Powered by Scholars. Published by Universities.®

2013

The Summer Undergraduate Research Fellowship (SURF) Symposium

Life Sciences

Proliferation

Articles 1 - 1 of 1

Full-Text Articles in Biomedical Engineering and Bioengineering

The Effects Of Exogenous Extracellular Matrix And Substrate Stiffness On Mouse Tendon Cells In Vitro, Caleb J. Mcdaniel, Sarah Calve Oct 2013

The Effects Of Exogenous Extracellular Matrix And Substrate Stiffness On Mouse Tendon Cells In Vitro, Caleb J. Mcdaniel, Sarah Calve

The Summer Undergraduate Research Fellowship (SURF) Symposium

To improve the treatment of musculoskeletal injuries, a better understanding of the transitional environment in which progenitor cells form mature musculoskeletal constructs is necessary. This need arises because injury repair requires restructuring of tissue, similar to the initial tissue construction that occurs during embryonic development by progenitor cells. Differences in both the biochemical and mechanical environments between a transitional and a differentiated state are known to take place, but how these differences affect cell behavior had not yet been characterized in mammalian tendon cells. In order to investigate this, we have determined the effects of exogenous extracellular matrix and the ...