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Full-Text Articles in Biomedical Engineering and Bioengineering

Muscular Properties And Balance Control In Older Adults, Christopher James Hasson Sep 2009

Muscular Properties And Balance Control In Older Adults, Christopher James Hasson

Open Access Dissertations

The goal of this dissertation was to understand the role of age-related changes in muscle mechanical properties in the control of upright posture in humans. First, a methodology for estimating subject-specific muscle properties in healthy young and older individuals was developed. Magnetic resonance and ultrasound imaging were used in conjunction with dynamometer experiments, musculoskeletal modeling, and numerical optimization to estimate the properties of the dorsiflexor and individual plantarflexor (gastrocnemius and soleus) muscles for 12 young and 12 older adults (balanced for gender). With aging there were declines in maximal isometric strength and increases in series-elastic stiffness in the male subjects, …


Functionalized Nanoparticles For Biological Imaging And Detection Applications, Bing C Mei Feb 2009

Functionalized Nanoparticles For Biological Imaging And Detection Applications, Bing C Mei

Doctoral Dissertations 1896 - February 2014

Semiconductor quantum dots (QDs) and gold nanoparticles (AuNPs) have gained tremendous attention in the last decade as a result of their size-dependent spectroscopic properties. These nanoparticles have been a subject of intense study to bridge the gap between macroscopic and atomic behavior, as well as to generate new materials for novel applications in therapeutics, biological sensing, light emitting devices, microelectronics, lasers, and solar cells. One of the most promising areas for the use of these nanoparticles is in biotechnology, where their size-dependent optical properties are harnessed for imaging and sensing applications. However, these nanoparticles, as synthesized, are often not stable …