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Full-Text Articles in Biomedical Engineering and Bioengineering

A Device For Noninvasive Assessment Of Vascular Impairment Risk In The Lower Extremity, Michael J. Hoffmann, Paul E. Knudson, M. Barbara Silver-Thorn Dec 2008

A Device For Noninvasive Assessment Of Vascular Impairment Risk In The Lower Extremity, Michael J. Hoffmann, Paul E. Knudson, M. Barbara Silver-Thorn

Biomedical Engineering Faculty Research and Publications

The repeatability and resolution of the clinical gold standard of vascular assessment, the ankle-brachial index (ABI), was compared to that of a new device that dynamically assesses tissue perfusion during external loading utilizing laser Doppler flowmetry. Eight subjects of varying levels of vascular impairment were tested in successive weeks using two different sites on the subject's posterior calf. These new measures included the perfusion decrease as well as the unloading delay during cyclic loading. Some new dynamic tissue perfusion measures demonstrated comparable levels of reproducibility with the ABI (e.g., 10%-20%). Only the unloading delay showed potentially enhanced resolution over ABI …


Parameter Estimation Of The Arterial System, James Charles Carter Ii Oct 2008

Parameter Estimation Of The Arterial System, James Charles Carter Ii

Mechanical & Aerospace Engineering Theses & Dissertations

There are a number of disorders that originate from or involve faulty operation of the cardiovascular system. Diseases such as atherosclerosis, diabetes and hypertension can have a debilitating effect on blood flow. This makes the tools for simulating the effects of such diseases on blood flow important. Measures, such as pulse wave velocity, that are generated by models of the cardiovascular system can be important indicators of cardiac health. Although physically measurable, obtaining some parameters comes with a high cost and discomfort to the patient. Models can provide an assessment of many important parameters. The purpose of this project was …