Biomedical Engineering and Bioengineering Commons^™

Axial Stent Strut Angle Influences Wall Shear Stress After Stent Implantation: Analysis Using 3d Computational Fluid Dynamics Models Of Stent Foreshortening, John F. Ladisa, Lars E. Olson, Douglas Anthony Hettrick, David C. Warltier, Judy R. Kersten, Paul S. Pagel

Biomedical Engineering Faculty Research and Publications

Introduction

The success of vascular stents in the restoration of blood flow is limited by restenosis. Recent data generated from computational fluid dynamics (CFD) models suggest that the vascular geometry created by an implanted stent causes local alterations in wall shear stress (WSS) that are associated with neointimal hyperplasia (NH). Foreshortening is a potential limitation of stent design that may affect stent performance and the rate of restenosis. The angle created between axially aligned stent struts and the principal direction of blood flow varies with the degree to which the stent foreshortens after implantation.

Methods

In the current investigation, we …

An Acoustic Fluid-Structure Simulation Of A Theraputic Ultrasound Wire Waveguide Apparatus, Graham Gavin, M.S. Hashmi, Finbar Dolan, Garrett Mcguinness

Conference Papers

The use of high-power low-frequency ultrasound transmitted down small diameter wire waveguides is an emerging technology that may have potential in the treatment of complicated atherosclerotic plaques in cardiovascular surgery. This form of energy delivery results in vibrating the distal-tip of the wire waveguide disrupting material by means of direct contact ablation and also cavitation, pressure waves and acoustic streaming in the surrounding fluid. This work describes a numerical acoustic fluid-structure model of the ultrasound wire waveguide and blood surrounding the distal tip. The structural analysis of the model predicts the natural frequencies of the waveguide and shows the extent …