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Biomedical Engineering and Bioengineering Commons™

Open Access. Powered by Scholars. Published by Universities.®

2003

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Articles 1 - 3 of 3

Full-Text Articles in Biomedical Engineering and Bioengineering

Atp-Independent Contractile Proteins From Plants, Michael Knoblauch, Gundula Noll, Torsten Müller, Dirk Prüfer, Ingrid Schneider-Hüther, Dörte Scharner, Aart Van Bel, Winfried Peters Aug 2003

Atp-Independent Contractile Proteins From Plants, Michael Knoblauch, Gundula Noll, Torsten Müller, Dirk Prüfer, Ingrid Schneider-Hüther, Dörte Scharner, Aart Van Bel, Winfried Peters

Winfried S. Peters

This paper has no abstract; this is the first paragraph. Emerging technologies are creating increasing interest in smart materials that may serve as actuators in micro- and nanodevices. Mechanically active polymers currently studied include a variety of materials. ATP-driven motor proteins, the actuators of living cells, possess promising characteristics, but their dependence on strictly defined chemical environments can be disadvantagous. Natural proteins that deform reversibly by entropic mechanisms might serve as models for artificial contractile polypeptides with useful functionality, but they are rare. Protein bodies from sieve elements of higher plants provide a novel example. sieve elements form microfluidics systems …

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Myocardial Recovery From Ischemia Is Impaired In Cd36-Null Mice And Restored By Myocyte Cd36 Expression Or Medium-Chain Fatty Acids., Glenn Gaudette, H Irie, I Krukenkamp, J Brinkmann, A Saltman, W Jou, J Glatz, N Abumrad, A Ibrahimi May 2003

Myocardial Recovery From Ischemia Is Impaired In Cd36-Null Mice And Restored By Myocyte Cd36 Expression Or Medium-Chain Fatty Acids., Glenn Gaudette, H Irie, I Krukenkamp, J Brinkmann, A Saltman, W Jou, J Glatz, N Abumrad, A Ibrahimi

Glenn R. Gaudette

Long-chain fatty acid uptake, which provides a large part of myocardial energy, is impaired in human and murine hearts deficient in the membrane fatty acid translocase, FAT/CD36. We examined myocardial function in CD36-null mice using the working heart. Fatty acid oxidation and stores of glycogen, triglycerides, and ATP were reduced in CD36-deficient hearts and were restored to WT levels by rescue of myocyte CD36. Under normal perfusion conditions, CD36-null hearts had similar cardiac outputs and end-diastolic pressures as WT or transgenic hearts. After 6 min of ischemia, cardiac output decreased by 41% and end diastolic pressure tripled for CD36-null hearts, …

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Apparatus For Illuminating The Tip-Sample Interface Of An Atomic Force Microscope, Nancy Burnham, E Thoreson Dec 2002

Apparatus For Illuminating The Tip-Sample Interface Of An Atomic Force Microscope, Nancy Burnham, E Thoreson

Nancy A. Burnham

An apparatus for the delivery of radiation to the tip-sample interface of an atomic force microscope(AFM) is demonstrated. The pulsed light delivery system (PLDS) was fabricated to probe photoinduced conformational changes of molecules using an AFM. The system is 67 mm long, 59 mm wide, and 21 mm high, leaving clearance to mount the PLDS and a microscope slide coated with a thin film of photoactive molecules beneath the cantilever tip of a stand-alone AFM. The PLDS is coupled into a fiber pigtailed Nd:yttrium–aluminum–garnetfrequency doubled laser, operating at a wavelength of 532 nm. The radiation delivered to a sample through …

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