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Biomedical Engineering and Bioengineering Commons

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2001

Chemical Engineering

Theses/Dissertations

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Full-Text Articles in Biomedical Engineering and Bioengineering

Effects Of Compression Processing Parameters And Antioxidants On Molecular Degradation Of Biodegradable Poly-L-Lactide (Plla), Thomas J. Hannan Jr. Jan 2001

Effects Of Compression Processing Parameters And Antioxidants On Molecular Degradation Of Biodegradable Poly-L-Lactide (Plla), Thomas J. Hannan Jr.

Masters Theses

The purpose of this research was to find a combination of poly (L-lactic acid), also known as poly-L-lactide or (PLLA) and antioxidants that would, together, produce a product whose degradation rate would be advantageous for use in biodegradable medical implants. Intrinsic viscosity tests were conducted on compression molded samples of PLLA that were molded at various processing parameters in order to find optimal parameters. The optimal processing parameters were found to be time 10 minutes, temperature 220°C, and pressure 1000 psi.

The molecular weight of PLLA sample was taken while pressure, time, and temperature were varied. As pressure increased, no …