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Full-Text Articles in Biomedical Engineering and Bioengineering

Modified Stent Design For A Coronary Bifurcation Lesion, Abigail Nowell May 2020

Modified Stent Design For A Coronary Bifurcation Lesion, Abigail Nowell

Biological Sciences Undergraduate Honors Theses

Currently, 18.2 million adults aged 20 and older are diagnosed with Coronary Artery Disease (CAD) (Benjamin et al., 2019). Stenosis is the most common intervention. However, when a patient has a bifurcated artery, treatment becomes more difficult and is often unsuccessful. This project created a new stent and balloon complex that was tested in vitro using a gel phantom artery model. Two separate prototypes have been created and tested so far, with improvements made upon each. Testing is still underway with Prototype 2.


Enhancement Of The Syncardia Total Artificial Heart For Pediatric Use, Margaret Clark, Madison Marks Jan 2020

Enhancement Of The Syncardia Total Artificial Heart For Pediatric Use, Margaret Clark, Madison Marks

Williams Honors College, Honors Research Projects

Pediatric patients with disorders and diseases of the heart have limited options with regards to implantable devices. Many of these implants are ventricular assist devices, which is not always suitable for a patient. Total artificial hearts (TAHs) have supported many adult patients until transplantation, and we believe that they could do the same for pediatric patients. SynCardia has the only Food and Drug Administration (FDA) approved TAH devices. Since SynCardia is the only company with FDA approved TAHs, we decided to modify the design of the SynCardia TAH for use in pediatric patients without compromising the function of the current …


Compressive Sensing Framework For Mass Spectrometry Data Analysis, Khalfalla Ahmad Kh. Awedat Apr 2016

Compressive Sensing Framework For Mass Spectrometry Data Analysis, Khalfalla Ahmad Kh. Awedat

Dissertations

Mass Spectrometry (MS) data is ideal for identifying unique bio-signatures of diseases. However, the high dimensionality of MS data hinders any promising MS-based proteomics development. The goal of this dissertation is to develop an accurate classification tool by employing compressive sensing (CS). Not only can CS significantly reduce MS data dimensionality, but it also will allow for full reconstruction of original data. The framework developed in this work is based on using L2 and a mixed L2-L1 norms, allowing an overdetermined system to be resolved. The results show that the L2- based algorithm with regularization terms has a better performance …


Spectral Analysis Of Pathological Acoustic Speech Waveforms, Priyanka Medida Jan 2009

Spectral Analysis Of Pathological Acoustic Speech Waveforms, Priyanka Medida

UNLV Theses, Dissertations, Professional Papers, and Capstones

Biomedical engineering is the application of engineering principles and techniques to the medical field. The design and problem solving skills of engineering are combined with medical and biological science, which improves medical disorder diagnosis and treatment. The purpose of this study is to develop an automated procedure for detecting excessive jitter in speech signals, which is useful for differentiating normal from pathologic speech. The fundamental motivation for this research is that tools are needed by speech pathologists and laryngologists for use in the early detection and treatment of laryngeal disorders. Acoustical analysis of speech was performed to analyze various features …