Biomedical Engineering and Bioengineering Commons^™

Fibers For Skin Regeneration, Astrid Michelle Rodriguez Negron

Theses and Dissertations

This thesis presents the successful development of biocompatible Polyvinyl Butyral (PVB), PVB/Polylysine and PVB/Tannic Acid (TA)/Polylysine fibers from an ethanol solution, Polyhydroxybutyrate (PHB), PHB/Polylysine, PHB/TA/Polylysine fibers from a chloroform solution and Chitosan (CH)/Pullulan (PL)/TA and CH/PL/TA/Polylysine fibers from an aqueous solution. The fibers were mass produced utilizing the Forcespinning® (FS) technology. The morphology of the fibers was characterized using a scanning electron microscope (SEM) and the fibers average diameter was calculated. The thermal properties of the fibers were characterized using a thermogravimetric analyzer (TGA) and a differential scanning calorimeter (DSC). The antibacterial activity of the fibers was assessed using against …