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Full-Text Articles in Biomedical Engineering and Bioengineering
Detecting And Screening Of The Prostate Cancer By Using An Optical Nanoporous Thin-Film Sensor, Salah Eldeen Mofleh Alzghoul
Detecting And Screening Of The Prostate Cancer By Using An Optical Nanoporous Thin-Film Sensor, Salah Eldeen Mofleh Alzghoul
Doctoral Dissertations
Prostate cancer (PC) affects elderly men more than young men. The currently used cancer biomarker, prostate-specific antigen (PSA), highly overestimates PC population. Men with high PSA levels often have to go through unnecessary, but physically painful, and expensive prosesses, such as prostate biopsies. Finding a prostate cancer marker that is produced selectively by cancer, but not by normal prostate cells will increase the reliability of PC test. In 2006, our collaborator (Dr. Girish Shah) discovered a novel protein, referred as neuroendocrine marker (NEM), secreted only by malignant prostate cells and released in blood circulation.
To examine whether the combined NEM-PSA …