Biomedical Engineering and Bioengineering Commons^™

Effects Of Scattering And Absorption On Laser Speckle Contrast Imaging, Kosar Khaksari

Dissertations, Master's Theses and Master's Reports

Laser Speckle Contrast Imaging (LSCI) is a real-time, non-invasive method in used to investigate blood flow and perfusion in biological tissues with high temporal and spatial resolution. A reduction in speckle contrast due to particle motion is the primary contrast mechanism in LSCI. Motion results in speckle fluctuations in time and reduces the contrast over a given camera integration period. There are a variety of parameters that effect contrast besides motion. The optical properties of the scattering medium are one of the parameters effecting LSCI values. Changes in blood hematocrit levels manifest as changes in optical properties. In this work, …