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Biomedical Engineering and Bioengineering Commons

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Theses/Dissertations

2001

Low and high memory load

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Encoding And Storage Components Of Verbal Working Memory As Revealed By A Factorial Design, An Fmri Study, Jason Steffener Aug 2001

Encoding And Storage Components Of Verbal Working Memory As Revealed By A Factorial Design, An Fmri Study, Jason Steffener

Theses

In this fMRI study, the contributions of frontal and posterior brain regions to verbal working memory were investigated. A two-factor design with low and high memory load (2 and 5 letters) and short and long delay (4 and 12 secs.) as factors were used. Based on reports in the literature, we expect activity in the following frontal and parietal brain regions of interest (ROIs): Brodmann areas (BA) 6, 9, 46, 44, 45, 7 and 40. The analysis of collected flvM data involved image processing and statistical analysis methods including realignment, spatial normalization, spatial smoothing, temporal filtering, intensity normalization, statistical tests, …