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The In Vitro Evaluation Of Various Biodegradable Composites Used In Internal Fixation Devices, Hui-Chen Hsieh
The In Vitro Evaluation Of Various Biodegradable Composites Used In Internal Fixation Devices, Hui-Chen Hsieh
Theses
In vitro degradation kinetics and mechanical properties of various composites, comprising a polycarbonate (DTE polymer) reinforced with CaP glass fiber, synthetic ceramic and non-ceramic hydroxyapatite (HA-500,OsteoGen HA) were investigated.
They were soaked in the SBF solution with a constant pH of 7.4 at 37°C for 5 days. The DTE/CaP composite degraded in an acid manner such that a large amount of NaOH was required but with a small decrease in calcium ion concentration. By contrast, the DTE/OsteoGen HA composite required comparable amounts of NaOH, but with a concomitantly large decrease in calcium ion concentration. This showed that the OsteoGen HA …