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Full-Text Articles in Biomedical Engineering and Bioengineering
Experimental Definition For Implantation Of The Afit Cortical Multielectrode Array, Adam G. Spenik
Experimental Definition For Implantation Of The Afit Cortical Multielectrode Array, Adam G. Spenik
Theses and Dissertations
A two-dimensional multiplexed array of 256 electrodes (16 x 16) has been fabricated using conventional CMOS fabrication techniques. The size and spacing of the electrodes (160 x 160 µm squares with center-to-center spacing of 250 µm) approximate that of the cortical columns. The device is mounted on a small biocompatible package and a protocol to implant this package on the visual cortex of a ferret and a Rhesus monkey was developed and approved. An instrumentation setup to record the data from the device is described as well as the methods used to demultiplex the data. Testing of the device in …
Development Of A Mammographic Image Processing Environment Using Matlab, John L. Kelley
Development Of A Mammographic Image Processing Environment Using Matlab, John L. Kelley
Theses and Dissertations
Breast cancer is a disease that accounts for a disturbingly large number of deaths in females each year. Its prevalence is a topic of concern to all of us since it can affect our families, friends, and coworkers. Although mammographic screening is the most effective method currently available for the early detection of breast cancer, it is far from being an infallible procedure. Mammographic reading is error prone, partly because of the complexity of the task and partly because of the variability in human performance. Computers offer high reproducibility, and when used as an adjunct by the radiologist, may improve …
Computer-Aided Breast Cancer Diagnosis, Catherine M. Kocur
Computer-Aided Breast Cancer Diagnosis, Catherine M. Kocur
Theses and Dissertations
This research advances computer-aided breast cancer diagnosis. More than 50 million women over the age of 40 are currently at risk from this disease in the United States. Computer-aided diagnosis is offered as a second opinion to radiologists to aid in decreasing the number of false readings of mammograms. This automated tool is designed to enhance detection and classification. New feature extraction methods are presented that provide increased classification power. Angular second moment, a second-order gray-level histogram statistic, provides baseline accuracy. Two novel extraction methods, eigenmass and wavelets, are introduced to the field. Based on the Karhunen-Loeve Transform, eigenmass features …
Characterization And Redesign Of The Afit Multielectrode Array, Richard G. Darenberg Jr.
Characterization And Redesign Of The Afit Multielectrode Array, Richard G. Darenberg Jr.
Theses and Dissertations
Since 1978, faculty and graduate students from the Air Force Institute of Technology (AFIT) have been working on an implantable circuit array that can record visual signals from the brain or stimulate the brain. In the current design the circuit is a 16 x 16 array of pads, each pad being 160 x 160 micrometers with 250 micrometers spacing with an 'L' shaped reference pad used as a ground reference. The array is multiplexed so that only one I-O line is required to access all 256 pads. This research was twofold: first to analyze the existing circuit and identify sources …
The Prediction Of Pilot Opinion Ratings Using Optimal And Sub-Optimal Pilot Models, Craig R. Edkins
The Prediction Of Pilot Opinion Ratings Using Optimal And Sub-Optimal Pilot Models, Craig R. Edkins
Theses and Dissertations
This study details the development of a sub-optimal pilot model that blended the classical and optimal pilot model approaches in an attempt to achieve the advantages of each. This model used a numerical solution to the linear quadratic Gaussian problem to find the pilot gain, lead, and lag values that minimized a performance index consisting of task error and control usage. This development was conducted in four phases. First, an optimal pilot model developed by Systems Technology, Incorporated, was analyzed in detail. This analysis included a step-by-step example problem to clarify the model's logic and an in-depth sensitivity analysis of …