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Full-Text Articles in Biomedical Engineering and Bioengineering

Novel Tools For Analysis Of Disordered Sleep And Motor Behavior In Preclinical Models Of Disease, Dillon M. Huffman Jan 2021

Novel Tools For Analysis Of Disordered Sleep And Motor Behavior In Preclinical Models Of Disease, Dillon M. Huffman

Theses and Dissertations--Biomedical Engineering

Subtle changes in sleep architecture can accompany and be symptomatic of various diseases or disorders. Understanding the complex interactions between sleep and health requires the ability to characterize sleep, probe its underlying mechanisms through perturbation, and quantify dependent physiological outcomes. Rodent models have come to be accepted as a valuable tool for preclinical investigations. However, experimental tools to accomplish such research typically rely on laborious methods that limit throughput and flexibility. Thus, research tools that minimize workload could be of great value to the research community and expedite investigation of the underlying mechanisms of sleep and further the development of …


Characterization Of Modulation And Coherence In Sensorimotor Rhythms Using Different Electroencephalographic Signal Derivations, Stephen Dundon Jan 2021

Characterization Of Modulation And Coherence In Sensorimotor Rhythms Using Different Electroencephalographic Signal Derivations, Stephen Dundon

Theses and Dissertations--Biomedical Engineering

Electroencephalography (EEG) is a widely used technique for monitoring and analyzing brain activity in experimental, diagnostic, and therapeutic applications. Since EEG is sensitive to noise and artefact sources, referential signals at different locations can be combined in different ways to improve signal quality and better localize cortical activity. Four signal derivations were compared against referential EEG in terms of their ability to measure the alpha rhythm modulation (or reactivity) and spatial coherence associated with an eye closure task: a common average reference (CAR), a local average reference (LAR), a large Laplacian (LL), and a focal Laplacian (FL) estimated using a …


Analysis Of Graded Sensorimotor Rhythms For Brain-Computer Interface Applications, Chase Allen Haddix Jan 2021

Analysis Of Graded Sensorimotor Rhythms For Brain-Computer Interface Applications, Chase Allen Haddix

Theses and Dissertations--Biomedical Engineering

The emerging field of neural engineering is tasked with applying engineering principles towards understanding neuroscience. A by-product of such a venture has been the development of a class of assistive devices known as brain-computer interfaces (BCIs) which link brain activity to actions performed by external devices. One application of this technology is in the rehabilitative sector for individuals with neuromuscular diseases and disorders. Despite tremendous efforts in the last few decades, a reliable signal that reflects fine motor control has yet to be adequately investigated. This gap in knowledge has limited the potential of BCIs to restore movement and communication. …


Changes In Cardiovascular, Respiratory, And Neural Activity By Music: Effects Of Breathing Pathway On Feeling Emotions, Mohammad Javad Mollakazemi Jan 2021

Changes In Cardiovascular, Respiratory, And Neural Activity By Music: Effects Of Breathing Pathway On Feeling Emotions, Mohammad Javad Mollakazemi

Theses and Dissertations--Biomedical Engineering

Listening to music can induce emotional and physiological changes. Increasing recognition of the palliative effects of music has led to its use as an adjuvant therapeutic tool in the treatment of various diseases. It is also well known that autonomic nervous activities and some cardiorespiratory rhythms change in correspondence with music. However, less is known about how these effects triggered by music come about. Listening to music affects synchronization between electroencephalograms (EEGs) and cardiac rhythmic activity. This interaction between cardiac and electrical responses led us to investigate whether EEG segments synchronized to different portions of the cardiac cycle can better …