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Full-Text Articles in Biomedical Engineering and Bioengineering
Using Electromagnetic Fields To Modulate The Self-Healing Capacity Of The Human Anterior Cruciate Ligament, Ryan M. Welsh
Mechanical Engineering Graduate Theses & Dissertations
A torn anterior cruciate ligament (ACL) is a notorious injury among athletes. Current means of replacement and reconstruction are ineffective and often result in instability and osteoarthritis. Tears in the medial collateral ligament (MCL), on the other hand, are self-healing and do not require surgical intervention. The differences between ACL and MCL healing properties have been shown to exist mainly on the cellular and biochemical levels. For example, ACL fibroblasts have shown increased production of and sensitivity to the cellular messenger nitric oxide (NO) in response to injury . Non-invasive enhancement of the self-healing capacity of ACL fibroblasts to more ...