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Biomedical Engineering and Bioengineering Commons

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Theses/Dissertations

Electronic Theses and Dissertations

University of Louisville

Other Biomedical Engineering and Bioengineering

2019

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Simulation Of A Continuum Tumor Model Using Distributed Computing., Dylan A Goodin Jul 2019

Simulation Of A Continuum Tumor Model Using Distributed Computing., Dylan A Goodin

Electronic Theses and Dissertations

Mathematical modeling aims to provide a theoretical framework for understanding tissue dynamics and for establishing treatment response for diseased tissues, such as tumors. Previously published continuum models have successfully represented idealized two-dimensional and three-dimensional tissue for short periods of time. A recently published continuum model of cancer increases model complexity and describes three-dimensional tissue that, due to the required complexity of the geometric multigrid solver, can only be feasibly applied to millimeter-scale simulations. Furthermore, the computational cost for such models has hindered their application in the laboratory and in the clinic. With computational demands greatly outpacing current openMP-based approaches on …