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Biomedical Engineering and Bioengineering Commons

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Theses/Dissertations

Electronic Theses and Dissertations

University of Denver

Computational modeling

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Full-Text Articles in Biomedical Engineering and Bioengineering

In Vivo Data Capture Using Hssr For Calibration Of Computational Models, Thor Erik Andreassen Jan 2020

In Vivo Data Capture Using Hssr For Calibration Of Computational Models, Thor Erik Andreassen

Electronic Theses and Dissertations

Computational modeling is a vital tool for understanding and evaluating healthy and unhealthy function of the musculoskeletal aspects of the human body. However, the accuracy of the musculoskeletal models depends significantly on the accuracy of the input data used to calibrate various behavioral parameters of the model. To date, most computational models have been built using generic in vitro data, mostly because of a lack of accurate and meaningful datasets from in vivo testing. The next major step in computational modeling is to create subject-specific computational models using calibration data taken from in vivo testing. The overall goal was to …


Computational Modeling Of Transcatheter Aortic Valves, Mostafa Abbasi Jan 2018

Computational Modeling Of Transcatheter Aortic Valves, Mostafa Abbasi

Electronic Theses and Dissertations

Transcatheter aortic valve replacement (TAVR) is an established therapy alternative to surgical valve replacement in high-risk and intermediate-risk patients with severe aortic stenosis. Currently, although TAVR is an alternative and less-invasive treatment for high-risk and intermediate-risk patients, surgical aortic valves replacement (SAVR) was still considered as the gold standard for low-risk patients. TAVR could potentially be applied to lower-risk younger patients if the indications can be safely expanded to the patients and transcatheter aortic valve (TAV) long-term durability can match with that of surgical bioprostheses. In contrast to surgical aortic valves (SAVs), there have been limited clinical data on the …