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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Engineering Nanomaterials For Imaging And Therapy Of Bacteria And Biofilm-Associated Infections, Akash Gupta
Engineering Nanomaterials For Imaging And Therapy Of Bacteria And Biofilm-Associated Infections, Akash Gupta
Doctoral Dissertations
Infections caused by multidrug-resistant (MDR) bacteria pose a serious global burden of mortality, causing thousands of deaths each year. The “superbug” risk is further exacerbated by chronic infections generated from antibiotic-resistant biofilms that are highly resistant to available treatments. Synthetic macromolecules such as polymers and nanoparticles have emerged as promising antimicrobials. Moreover, ability to modulate nanomaterial interaction with bacterial cellular systems plays a pivotal role in improving the efficacy of the strategy. In the initial studies on engineering nanoparticle surface chemistry, I investigated the role played by surface ligands in determining the antimicrobial activity of the nanoparticles. In further study, …
Characteristics And Functionalities Of Natural And Bioinspired Nanomaterials, Lijin Xia
Characteristics And Functionalities Of Natural And Bioinspired Nanomaterials, Lijin Xia
Doctoral Dissertations
Green nanoscience is a rapidly emerging field that aims to achieve the maximum performance and benefits from nanotechnology, while minimizing the impact on the environment. In this study, several methods for the green nanomanufacturing of biomedically important nanomaterials, specifically through the use of natural plants, have been extensively investigated. It was found that natural nanomaterials are inherent within plants, and can be further manipulated for potential biomedical applications. In addition, the metabolites and reductive capacity of plant extracts can be used to synthesize metallic nanoparticles with advantages over semi-conductor based nanomaterials. Nanoparticles were found to exist in the extracts produced …
Integration Of Micro Nano And Bio Technologies With Layer -By -Layer Self -Assembly, Dinesh Shankar Kommireddy
Integration Of Micro Nano And Bio Technologies With Layer -By -Layer Self -Assembly, Dinesh Shankar Kommireddy
Doctoral Dissertations
In the past decade, layer-by-layer (LbL) nanoassembly has been used as a tool for immobilization and surface modification of materials with applications in biology and physical sciences. Often, in such applications, LbL assembly is integrated with various techniques to form functional surface coatings and immobilized matrices. In this work, integration of LbL with microfabrication and microfluidics, and tissue engineering are explored. In an effort to integrate microfabrication with LbL nanoassembly, microchannels were fabricated using soft-lithography and the surface of these channels was used for the immobilization of materials using LbL and laminar flow patterning. Synthesis of poly(dimethyldiallyl ammonium chloride)/poly(styrene sulfonate) …