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Full-Text Articles in Biomedical Engineering and Bioengineering
Effect Of Size Reduction Parameters In Pharmaceutical Manufacturing Process, Brian Breneman
Effect Of Size Reduction Parameters In Pharmaceutical Manufacturing Process, Brian Breneman
Biomedical Engineering
Within pharmaceutical manufacturing, size reduction is one of the most extensively used and vital unit operations. Size reduction in tablet production is achieved primarily through milling procedures, which allows for attaining product uniformity, optimizing product solubility, and improving bioavailability. Additionally, powders with a narrow range of size distribution can obviate problems in downstream processing as pertains to blending, compression, and coating as well as improve drug performance1. The purpose this study was to characterize the effect of various size reduction parameters as a result of the pharmaceutical milling process on a lactose wet granulation formulation and chemically active …
An Inexpensive Method For Creating Paste To Be Used In Paper-Based Microfluidic Devices, Kirra Marie Sankey
An Inexpensive Method For Creating Paste To Be Used In Paper-Based Microfluidic Devices, Kirra Marie Sankey
Biomedical Engineering
Microfluidic devices are diagnostic tools that are small, portable, and inexpensive. This makes them ideally suited for resource-limited settings. To construct a 3D device, each layer of patterned paper is stacked using double-sided tape with holes corresponding to the pattern. It is necessary to have a paste to fill the holes in the tape and provide a medium for the fluid to wick through. The powder used to make the paste is very expensive and must be bought in bulk (an estimated $1121 - $1231), so it is not convenient for the Biomedical (BMED) department to use. This project was …