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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Mechanical And Physical Properties Of Spider Silk Films Made From Organic And Water-Based Dopes, Chauncey Lewis Tucker
Mechanical And Physical Properties Of Spider Silk Films Made From Organic And Water-Based Dopes, Chauncey Lewis Tucker
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Spider silk has become a popular material due to its exceptional mechanical and biocompatibility properties. The project team has developed methods of producing and improving the properties of synthetic spider silk films. Other groups have been able to produce similar films having less than impressive mechanical properties using a toxic solvent. The spider silk team here at Utah State University has developed a new way of processing these films to more than triple their mechanical properties and has created a novel form of spider silk films produced from a water-based liquid, making it less expensive, more environmentally friendly, and more …
A Synthetic Biological Engineering Approach To Secretion- Based Recovery Of Polyhydroxyalkanoates And Other Cellular Products, Elisabeth Linton
A Synthetic Biological Engineering Approach To Secretion- Based Recovery Of Polyhydroxyalkanoates And Other Cellular Products, Elisabeth Linton
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
The costs associated with cellular product recovery commonly account for as much as 80% of the total production expense. As a specific example, significant recovery costs limit commercial use of polyhydroxyalkanoates (PHA), which comprise a class of microbially-accumulated polyesters. PHAs are biodegradable compounds that are of interest as a sustainable alternative to petrochemically-derived plastics. Secretion-based recovery of PHAs was studied to decrease PHA production costs. Type I and II secretory pathways are commonly used for the translocation of recombinant proteins out of the cytoplasm of E. coli. Proteins were targeted for translocation using four signal peptides (HlyA, TorA, GeneIII, …