Biomedical Engineering and Bioengineering Commons^™

Two-Dimensional Computer Model Of Human Atrial Ablation, Samineh R. Esfahani

USF Tampa Graduate Theses and Dissertations

A finite-element model of a two-dimensional slice of human atrial tissue for the study of the electrograms and propagation of action potentials is presented. Action potential propagation is described by a reaction-diffusion model coupled with the complex Courtemanche et al. atrial cell model. The effects of recording electrode size and location on electrograms are presented. Action potential propagation as a result of atrial fibrillation ablation therapy is also modeled by defining a lesion area with decreased electrical conductivity. The effect of electrical conductivity and geometry of the lesion was also studied. It is shown that the success rate of atrial …