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Therapeutic Potential Of Catechins And Derivatives For The Prevention Of Alzheimer’S Disease, Shelby Elaine Chastain
Therapeutic Potential Of Catechins And Derivatives For The Prevention Of Alzheimer’S Disease, Shelby Elaine Chastain
Theses and Dissertations
Alzheimer’s disease (AD) is a neurodegenerative condition that affects 1 in 9 people over the age of 65, an estimated 5.4 million Americans. It is the only disease among the top 10 that cannot be prevented, cured, or treated. Based on the lack of a viable therapeutic for the prevention or cure of AD, it is vital that therapeutic research for AD continues. AD is characterized by the deposition of extracellular neuritic plaques comprised of insoluble amyloid-β (Aβ) fibrils. These plaques are formed from the amyloidogenic aggregation of Aβ monomer, generated from the cleavage of the amyloid precursor protein (APP) …