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Biomedical Engineering and Bioengineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Theses/Dissertations

University of Denver

Biomechanics and Biotransport

Center for Orthopaedic Biomechanics

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Full-Text Articles in Biomedical Engineering and Bioengineering

Mechanical Effects Of Surgical Adhesives On Ascending Thoracic Aortic Aneurysm Replacement, Dong Qiu Jan 2017

Mechanical Effects Of Surgical Adhesives On Ascending Thoracic Aortic Aneurysm Replacement, Dong Qiu

Electronic Theses and Dissertations

Ascending thoracic aortic aneurysm (aTAA) is a potentially lethal disease which grows gradually over time and may lead to aortic dissection and rupture. Currently, aTAA surgical repair using Dacron graft is a well-established treatment. In addition, surgical adhesives are frequently used in the surgeries to seal the anastomotic site. This study aims to investigate mechanical effects of four commonly used surgical adhesives, namely BioGlue, CoSeal, Crosseal, and Tisseel, on the suture site using in-vitro digital image correlation (DIC) method and finite element (FE) simulations in an ovine model. In this study, first, mechanical properties of ovine ascending aorta were obtained …


Statistical Shape And Intensity Modeling Of The Shoulder, Irene Sintini Jan 2017

Statistical Shape And Intensity Modeling Of The Shoulder, Irene Sintini

Electronic Theses and Dissertations

Anatomical variability in the shoulder is inherently present and can influence healthy and pathologic biomechanics and ultimately clinical decision-making. Characterizing variation in bony morphology and material properties in the population can support treatment and specifically the design, via shape and sizing, of shoulder implants. Total Shoulder Arthroplasty (TSA) is the treatment of choice for glenohumeral osteoarthritis as well as bone fracture. Complications and poor outcomes in TSA are generally influenced by the inability of the implant to replicate the natural joint biomechanics and by the bone quality around the fixation features. For this reason, knowledge of bony morphology and mechanical …