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Biomedical Engineering and Bioengineering Commons

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Theses/Dissertations

Michigan Technological University

Biology and Biomimetic Materials

Magnetoelastic

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Full-Text Articles in Biomedical Engineering and Bioengineering

Studying Mass And Mechanical Property Changes During The Degradation Of A Bioadhesive With Mass Tracking, Rheology And Magnetoelastic (Me) Sensors, Zhongtian Zhang Jan 2018

Studying Mass And Mechanical Property Changes During The Degradation Of A Bioadhesive With Mass Tracking, Rheology And Magnetoelastic (Me) Sensors, Zhongtian Zhang

Dissertations, Master's Theses and Master's Reports

In this research, the degradable polymer 4-arm poly (ethylene glycol)-glutaric acid-dopamine (PEG-GA-DM4) was synthesized. The degradation behavior of crosslinked PEG-GA-DM4 bioadhesive was studied with mass tracking, oscillatory rheology, and magnetoelastic (ME) sensors. Changes in mechanical properties were correlated with both dry mass and wet mass changes during the degradation. The results indicate that the loss of mechanical property in the bioadhesive can take place without losing the dry mass. The mass loss profile cannot describe the degradation behavior completely. In addition to studying the degradation of PEG-GA-DM4, this research also confirms the application of ME …