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Biomedical Engineering and Bioengineering Commons

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Theses/Dissertations

Life Sciences

Wayne State University Dissertations

2011

Neurotrauma

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A Multi-Species Analysis Of Biomechanical Responses Of The Head To A Shock Wave, Richard Bolander Jan 2011

A Multi-Species Analysis Of Biomechanical Responses Of The Head To A Shock Wave, Richard Bolander

Wayne State University Dissertations

Shock wave induced brain injury remains a field of research that has great consequences for the rehabilitation of soldiers and civilians that are exposed to an explosion. As such, for the research to be successful in developing strategies to mitigate the effects of these injuries, appropriate research methods need to be developed. Animal models are currently employed to understand the brain's response to a shock wave exposure. Unfortunately no criteria have been established that indicates in what way the mechanical inputs that the cells in an animal's brain are subjected to are similar to a human. The purpose of this …