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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Quantifying And Reversing Compensatory Movements By Persons Post-Stroke In The Ambient Setting, Aaron Miller Dec 2021

Quantifying And Reversing Compensatory Movements By Persons Post-Stroke In The Ambient Setting, Aaron Miller

Doctoral Dissertations

Nearly 800,000 people in the United States suffer stroke annually. Following the onset of stroke, survivors will exhibit deficits, such as hemiplegia, which will limit their function and ability to perform activities of daily living (ADLs). In order to regain independence, many stroke survivors will employ maladaptive compensatory strategies to help with the completion of tasks. Compensation is generally defined as any performance of a task that is different than the way it may have been performed before the onset of a neurodegenerative disorder. While for some severely impaired individuals, compensation may be necessary, for most these maladaptive strategies ultimately …


Enhancing Biomechanical Function Through Development And Testing Of Assistive Devices For Shoulder Impairment And Total Limb Amputation, Patrick Hall Aug 2021

Enhancing Biomechanical Function Through Development And Testing Of Assistive Devices For Shoulder Impairment And Total Limb Amputation, Patrick Hall

Doctoral Dissertations

Assistive devices serve as a potential for restoring sensorimotor function to impaired individuals. My research focuses on two assistive devices: a passive shoulder exoskeleton and a muscle-driven endoprosthesis (MDE). Previous passive shoulder exoskeletons have focused on testing during static loading conditions in the shoulder. However, activities of daily living are based on dynamic tasks. My research for passive shoulder exoskeletons analyzes the effect that a continuous passive assistance has on shoulder biomechanics. In my research I showed that passive assistance decreases the muscular activation in muscles responsible for positive shoulder exoskeleton. An MDE has the potential to have accurate and …


Surface Enhanced Raman Spectroscopy (Sers) As An Approach For The Emerging Liquid Biopsy Diagnostics, Nariman Banaei Jun 2021

Surface Enhanced Raman Spectroscopy (Sers) As An Approach For The Emerging Liquid Biopsy Diagnostics, Nariman Banaei

Doctoral Dissertations

Large Molecule bioanalysis and biosensor development are essential techniques that are required in many applications, including biotherapeutic development, in vitro diagnostic, biomarker detection, and early detection. These techniques should be highly specific and sensitive enough to identify and quantify an analyte of interest with minimum sample pretreatment requirements. This work explores the development and application of chip-scale bioassays based on surface-enhanced Raman scattering (SERS). It introduces sensing techniques to quantify various disease biomarkers, specifically pancreatic cancer. Blood is the best source of information about our body's function. There are many biomarkers in the blood, and each biomarker's high expression level …


Non-Contact Techniques For Human Vital Sign Detection And Gait Analysis, Farnaz Foroughian May 2021

Non-Contact Techniques For Human Vital Sign Detection And Gait Analysis, Farnaz Foroughian

Doctoral Dissertations

Human vital signs including respiratory rate, heart rate, oxygen saturation, blood pressure, and body temperature are important physiological parameters that are used to track and monitor human health condition. Another important biological parameter of human health is human gait. Human vital sign detection and gait investigations have been attracted many scientists and practitioners in various fields such as sport medicine, geriatric medicine, bio-mechanic and bio-medical engineering and has many biological and medical applications such as diagnosis of health issues and abnormalities, elderly care and health monitoring, athlete performance analysis, and treatment of joint problems. Thoroughly tracking and understanding the normal …