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Full-Text Articles in Biomedical Engineering and Bioengineering
Effective Estimation And Computer Control Of Minimum Tumour Temperature During Conductive Interstitial Hyperthermia, J A. Deford, Charles F. Babbs, U H. Patel, M W. Bleyer, J A. Marchosky, C J. Moran
Effective Estimation And Computer Control Of Minimum Tumour Temperature During Conductive Interstitial Hyperthermia, J A. Deford, Charles F. Babbs, U H. Patel, M W. Bleyer, J A. Marchosky, C J. Moran
Weldon School of Biomedical Engineering Faculty Publications
The goal of heat therapy in the treatment of malignant disease is to raise the temperature of all neoplastic tissue to a cytotoxic temperature for a predetermined period of time. This seemingly simple task has proved difficult in-vivo, in part because of nonuniform power absorption and in part because of nonhomogeneous and time varying tumour blood flow. We have addressed this difficulty first by utilizing the conceptually simple technique of conductive interstitial hyperthermia, in which the tumour is warmed by multiple, electrically heated catheters, and second by implementing on-line conu·ol of minimum tumour temperatures near each catheter, estimated on the …
Regional Blood Flow During Cardiopulmonary Resuscitation With Abdominal Counterpulsation In Dogs, William D. Voorhees Iii, Sandra H. Ralston, Charles F. Babbs
Regional Blood Flow During Cardiopulmonary Resuscitation With Abdominal Counterpulsation In Dogs, William D. Voorhees Iii, Sandra H. Ralston, Charles F. Babbs
Weldon School of Biomedical Engineering Faculty Publications
The addition of abdominal counterpulsation to standard cardiopulmonary resuscitation (IAC-CPR) during ventricular fibrillation has been shown to improve cardiac output, oxygen uptake, and central arterial blood pressure in dogs. The present study was performed to determine the effect of IAC-CPR on regional blood flow. Regional blood flow was measured with radioactively labeled microspheres during sinus rhythm and during alternate periods of IAC-CPR and standard CPR (STD-CPR) in nine dogs anesthetized with pentobarbital. Blood pressures and oxygen uptake were measured continuously. As in previous studies, diastolic arterial pressure was higher (30.8%) during IAC-CPR than during STD-CPR, as were cardiac output (24.5%) …