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Weldon School of Biomedical Engineering Faculty Publications

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Full-Text Articles in Biomedical Engineering and Bioengineering

A Potential New Technique To Estimate The Origins Of Focal Atrial Tachycardias From 12-Lead Electrocardiograms, Charles F. Babbs Jan 2016

A Potential New Technique To Estimate The Origins Of Focal Atrial Tachycardias From 12-Lead Electrocardiograms, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

Background: This brief report presents a potential new technique for locating the sites of origin of focal atrial tachycardias from standard 12-lead electrocardiograms. Methods: Estimated P wave vector coordinates are derived from leads I, aVF, V1 and V2, and mapped to a three dimensional coordinate system in space. A simple graphical method is used to find the back projection of the P wave vector onto the surface of atrial muscle to estimate the most likely site of origin of the tachycardia. Results: Graphical back projection correctly identified foci of atrial tachycardias in 19 of 19 cases described in the most …


Effective Estimation And Computer Control Of Minimum Tumour Temperature During Conductive Interstitial Hyperthermia, J A. Deford, Charles F. Babbs, U H. Patel, M W. Bleyer, J A. Marchosky, C J. Moran Jan 1991

Effective Estimation And Computer Control Of Minimum Tumour Temperature During Conductive Interstitial Hyperthermia, J A. Deford, Charles F. Babbs, U H. Patel, M W. Bleyer, J A. Marchosky, C J. Moran

Weldon School of Biomedical Engineering Faculty Publications

The goal of heat therapy in the treatment of malignant disease is to raise the temperature of all neoplastic tissue to a cytotoxic temperature for a predetermined period of time. This seemingly simple task has proved difficult in-vivo, in part because of nonuniform power absorption and in part because of nonhomogeneous and time varying tumour blood flow. We have addressed this difficulty first by utilizing the conceptually simple technique of conductive interstitial hyperthermia, in which the tumour is warmed by multiple, electrically heated catheters, and second by implementing on-line conu·ol of minimum tumour temperatures near each catheter, estimated on the …