Biomedical Engineering and Bioengineering Commons^™

An Investigation Of The Biomechanical Response From Shock Wave Loading To The Head, Alessandra Dal Cengio Leonardi

Wayne State University Dissertations

There is a pressing need for a comprehensive explanation of the mechanism of brain injury after exposure to blast and several hypotheses have been suggested. The focus of this research was to investigate one of the hypotheses for primary brain injury due to blast: multimodal skull flexure. The significance of this research is twofold. First, resolution of the mode of energy transfer and of the induced stresses within the skull-brain system will allow for creations of mitigation/protective techniques/equipment, as well as design of experiments investigating live-cell response using more reliable physical models. Second, the data obtained experimentally will be available …