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Biomedical Engineering and Bioengineering Commons™
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- ANOVA (1)
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- Drug releasing hydrogels (1)
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Articles 1 - 4 of 4
Full-Text Articles in Biomedical Engineering and Bioengineering
Drug Releasing Hydrogels For Opioid Use Disorder, Kaytlyn M. Crowe
Drug Releasing Hydrogels For Opioid Use Disorder, Kaytlyn M. Crowe
Theses
Ease of access to prescription opioids and the strength of synthetic opioids have contributed to the rise in over use disorders, overdose, and death rates during the opioid epidemic. The current overdose standard of care, rescue NLX (NLX), is a competitive antagonist to the μ-opioid receptor but has a relatively short period of action compared to opioid agonists, especially synthetic agonists. Rises in the abuse of these synthetic and semi-synthetic agents in recent years have shown the weaknesses of rescue NLX, as it can leave overdose patients vulnerable to renarcotization and precipitated withdrawal. To prevent both from occurring, we developed …
The Effects Of Design Parameters On The Neural Recordings With Micro-Ecog Arrays, Manan Amish Sethia
The Effects Of Design Parameters On The Neural Recordings With Micro-Ecog Arrays, Manan Amish Sethia
Theses
In the field of neural prosthetics, electro-cortico-graph (ECoG) arrays are commonly used to record neural activity of the brain cortex both in animal and human subjects. A finite element model (FEM) was developed to simulate the electric field generated by a single neuron in the rat brain cortex and a micro ECoG array (µECoG) placed on the pia surface for recording the neural signal. The neuron was simulated as a dipole current source with a magnitude of 1µA and placed at three different depths in the motor cortex corresponding to different layers under the µECoG array. The array design was …
Real Time Analysis Of Eye Movements Using Computer Aided Software, Farhan Ahmad
Real Time Analysis Of Eye Movements Using Computer Aided Software, Farhan Ahmad
Theses
Eye movement analysis is a slow and tasking job that require a trained vision analyst to sift through hundreds of eye movements. The difficulty of the task increases when a subject has undiagnosed eye related disorders. One such disorder is Convergence insufficiency (CI) which affects nearly 12 million people in the US. Convergence insufficiency occurs when the eyes are unable to coordinate simultaneous inward movement for near focal tracking. Individuals with CI are unable to coordinate eye movements this can result in many symptoms such as double vision, blurred vision, headaches, vision strain, and fatigue. A diagnosis for CI relies …
Neurovascular Catheter Measurement System Development For Process And Design Effect Evaluation, Cathal Tadhg Merz
Neurovascular Catheter Measurement System Development For Process And Design Effect Evaluation, Cathal Tadhg Merz
Theses
Neurovascular guide catheters are used to treat problems affecting blood vessels within the brain through minimally invasive procedures. Catheters are inserted into the patient via their femoral or brachial arteries and manually navigated to the brain to deliver treatment. This procedure replaces the requirement to cut into the patient’s skull and brain tissue but is limited by reduction of blood vessel lumen diameter and increase in tortuosity of blood vessels deep in the brain. During these procedures, catheters can sometimes fail by kinking or fracturing into two pieces. The rate of failure by fracture of a particular neurovascular catheter device …