Biomedical Engineering and Bioengineering Commons^™

Sol-Gel Derived Bioceramic Poly(Diethyl Fumarate – Co – Triethoxyvinylsilane) Composite, Aref Sleiman

Electronic Thesis and Dissertation Repository

Synthetic bone graft materials have become an increasingly popular choice for bone augmentation. Ceramic-based and polymer-based bone graft materials constitute the two main classes of synthetic bone graft materials. This study investigated the synthesis of novel bioactive composites for their potential use as bone graft biomaterials. Poly(diethyl fumarate-co-triethoxyvinylsilane)/bioceramic class II organic/inorganic hybrid biomaterials were synthesized via a sol gel process. These biomaterials were then reacted with an ammonium phosphate solution to prepare their respective composites. For the first time, we successfully synthesized sol-gel derived bioceramic poly(diethyl fumarate-co-triethoxyvinylsilane) composites. In vitro bioactivity evaluation of poly(diethyl fumarate-co-triethoxyvinylsilane)/bioceramic composites in simulated body fluid …