Biomedical Engineering and Bioengineering Commons^™

Continuous Size-Based Separation Of Microparticles In A Microchannel With Symmetric Sharp Corner Structures, Liang-Liang Fan, Xu-Kun He, Yu Hun, Li Du, Liang Zhao, Jiang Zhe

Dr. Jiang Zhe

A new microchannel with a series of symmetric sharp corner structures is reported for passive size-dependent particle separation. Micro particles of different sizes can be completely separated based on the combination of the inertial lift force and the centrifugal force induced by the sharp corner structures in the microchannel. At appropriate flow rate and Reynolds number, the centrifugal force effect on large particles, induced by the sharp corner structures, is stronger than that on small particles; hence after passing a series of symmetric sharp corner structures, large particles are focused to the center of the microchannel, while small particles are …