Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Applied sciences (2)
- Applied math (1)
- Bone model reconstruction x-ray radiography (1)
- Cartilage (1)
- Computer vision (1)
-
- Control release (1)
- Control theory (1)
- Ensemble empirical mode decomposition (1)
- Epilpsy (1)
- Halloysite (1)
- Intrinsic mode function (1)
- Knee (1)
- Modeling (1)
- Nanocomposite (1)
- ODE (1)
- Optimization (1)
- Osteoarthritis (1)
- PDE (1)
- Predictive modeling (1)
- Pure sciences (1)
- Segmentation (1)
- Seizure anticipation (1)
- Seizure prediction (1)
- Synchronization (1)
- Toxoplasma gondii (1)
Articles 1 - 6 of 6
Full-Text Articles in Biomedical Engineering and Bioengineering
Analysis, Segmentation And Prediction Of Knee Cartilage Using Statistical Shape Models, Joseph Michael Johnson
Analysis, Segmentation And Prediction Of Knee Cartilage Using Statistical Shape Models, Joseph Michael Johnson
Doctoral Dissertations
Osteoarthritis (OA) of the knee is one of the leading causes of chronic disability (along with the hip). Due to rising healthcare costs associated with OA, it is important to fully understand the disease and how it progresses in the knee. One symptom of knee OA is the degeneration of cartilage in the articulating knee. The cartilage pad plays a major role in painting the biomechanical picture of the knee. This work attempts to quantify the cartilage thickness of healthy male and female knees using statistical shape models (SSMs) for a deep knee bend activity. Additionally, novel cartilage segmentation from …
Reconstruction Of Patient-Specific Bone Models From X-Ray Radiography, Hatem Amin Abdel Fattah El Dakhakhni
Reconstruction Of Patient-Specific Bone Models From X-Ray Radiography, Hatem Amin Abdel Fattah El Dakhakhni
Doctoral Dissertations
The availability of a patient‐specific bone model has become an increasingly invaluable addition to orthopedic case evaluation and planning [1]. Utilized within a wide range of specialized visualization and analysis tools, such models provide unprecedented wealth of bone shape information previously unattainable using traditional radiographic imaging [2]. In this work, a novel bone reconstruction method from two or more x‐ray images is described. This method is superior to previous attempts in terms of accuracy and repeatability. The new technique accurately models the radiological scene in a way that eliminates the need for expensive multi‐planar radiographic imaging systems. It is also …
Modeling And Control Of Nanoparticle Bloodstream Concentration For Cancer Therapies, Scarlett S. Bracey
Modeling And Control Of Nanoparticle Bloodstream Concentration For Cancer Therapies, Scarlett S. Bracey
Doctoral Dissertations
Currently, the most commonly used treatments for cancerous tumors (chemotherapy, radiation, etc.) have almost no method of monitoring the administration of the treatment for adverse effects in real time. Without any real time feedback or control, treatment becomes a "guess and check" method with no way of predicting the effects of the drugs based on the actual bioavailability to the patient's body. One particular drug may be effective for one patient, yet provide no benefit to another. Doctors and scientists do not routinely attempt to quantifiably explain this discrepancy. In this work, mathematical modeling and analysis techniques are joined together …
Halloysite Nanotube Composites For Sustained Release Of Antimocrobial Agents (Antiseptics And Antibiotics), Wenbo Wei
Doctoral Dissertations
Encapsulation of antimicrobial agents (simple antiseptics and more specific antibiotics) within micro-scale and nano-scale containers may provide prolonged and more evenly distributed drug release. One of such containers proposed at Louisiana Tech is natural halloysite clay nanotubes. Halloysite is an aluminosilicate tube with a length of approximately 1 µm, outer diameter of approximately 50 nm, and internal lumen of 15 nm. The chemical composition of halloysite is similar to more common clay–kaolinite, and it can be described as rolled sheets of kaolinite. Halloysite, loaded with drugs inside its lumen, has shown aqueous release of the loaded chemicals over 10-20 hours …
Multiscale Modeling Of Toxoplasma Gondii, Adam Michael Sullivan
Multiscale Modeling Of Toxoplasma Gondii, Adam Michael Sullivan
Doctoral Dissertations
Toxoplasma gondii is a potentially deadly parasite that uses a very unique way of manipulating the cell and immune systems. To investigate the mechanics of how the parasite spreads within hosts, several interwoven topics related to the study of within-host dynamics of Toxoplasma gondii are presented here. Understanding the complicated methods of how the parasite grows, dies, invades, replicates, and evades the host immune response is the critical aim of this independent research. Understanding the processes of acute and chronic infection are studied independently, followed by modeling the two processes in the same model. Finally, the dynamic models are simulated …
Intrinsic Mode Function Synchronization Measures For The Anticipation Of Seizures In Epilpsy, Daniel William Moller
Intrinsic Mode Function Synchronization Measures For The Anticipation Of Seizures In Epilpsy, Daniel William Moller
Doctoral Dissertations
Epileptic seizures affect as many as 50 million people and often occur without warning or apparent provocation. We explore the applicability of noise-assisted Ensemble Empirical Mode Decomposition (EEMD) for patient-specific seizure anticipation synchronization measures as applied to the EEMD intrinsic mode function (IMF) output. Intracranial EEG data were obtained from pre-surgical monitoring at the Epilepsy Center of the University Hospital of Freiburg. Data from twenty patients were analyzed. For each recorded channel, non-overlapping time windows were submitted to the EEMD algorithm, producing twelve levels of IMFs. IMF synchronization measures (mean and maximum coherence, mean and maximum cross-correlation, correlation coefficient and …