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Novel Mechanisms Of Dc And Kilohertz Electrical Stimulation, Zeinab Esmaeilpour
Novel Mechanisms Of Dc And Kilohertz Electrical Stimulation, Zeinab Esmaeilpour
Dissertations and Theses
Transcranial electrical stimulation is a promising technique where a weak electrical current is applied to the scalp with the goal of modulating brain activity. Understanding the cellular mechanism of direct current (DC) and kilohertz (kHz) electrical stimulation is of broad interest in neuromodulation. More specifically, there is a large mismatch between enthusiasm for clinical applications of the method and understanding of DC and kHz novel mechanisms of action. This dissertation is centered around two main fundamental aims: 1) systematic study of the acute and long-term effects of kilohertz electrical stimulation and amplitude-modulated waveform with kHz carrier frequency using a well-established …