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Biomedical Engineering and Bioengineering Commons

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Cells and Materials

1993

Biodegradation

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In-Vivo Reactions In Some Bioactive Glasses And Glass-Ceramics Granules, A. M. Gatti, T. Yamamuro, L. L. Hench, O. H. Andersson Jan 1993

In-Vivo Reactions In Some Bioactive Glasses And Glass-Ceramics Granules, A. M. Gatti, T. Yamamuro, L. L. Hench, O. H. Andersson

Cells and Materials

Two different bioactive glasses and one glass-ceramic were implanted as granules for 2 months in rabbit muscle and for 5 months in sheep jaw in order to study the influence of the biological surroundings on the reactions of the materials.

Scanning electron microscope and energy dispersive X-ray microanalysis showed that a calcium and phosphorous-rich (CaP) surface layer (adjacent to a silicon rich-layer) forms on both glasses in both implantation sites. The glass-ceramic developed only a CaP layer. A chemical process of degradation was more evident in muscle, even though the implantation time was shorter than that in bone. For all …