Biomedical Engineering and Bioengineering Commons^™

Development Of A Model For Accelerated Fatigue Testing In Venous Valves, Olga Brazhkina

Biomedical Engineering Undergraduate Honors Theses

Malfunctioning venous cause issues ranging from cosmetic to life threatening situations for millions of people in the U.S. (1). Venous valve bioprosthetics often fail due to a loss in leaflet tissue flexibility following chemical fixation of donor tissue (2). A viable solution for testing venous valves prior to and post chemical fixation is in high demand for the development of a more durable prosthetic replacement. As a result, this research aims to create a fatigue apparatus that provides a means to model the durability of venous valves. The design criteria for this project included modeling physiological conditions in an accelerated …